1-(5-Methyl-7,8-dihydro-benzo[c]phenanthren-6-yl)-ethanone | 868840-06-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 1-(5-Methyl-7,8-dihydro-benzo[c]phenanthren-6-yl)-ethanone
• 英文别名: 1-(5-Methyl-7,8-dihydrobenzo[c]phenanthren-6-yl)ethanone；1-(5-methyl-7,8-dihydrobenzo[c]phenanthren-6-yl)ethanone
• CAS: 868840-06-6
• 化学式: C₂₁H₁₈O
• 分子量: 286.373
• InChiKey: FWBDUOAMZZWRCL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-(5-Methyl-7,8-dihydro-benzo[c]phenanthren-6-yl)-ethanone 在 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 苯 为溶剂， 反应 72.0h， 以80%的产率得到1-(5-Methyl-benzo[c]phenanthren-6-yl)-ethanone
  参考文献：
  名称：

  Photo-induced aromatic assembly of benzocycloalka[1,2-b] furan and spiro[furan-2(3H),1′-benzocycloalkane] derivatives

  摘要：

  The photo-induced benzannulation of benzocycloalka[1,2-b]furans produced hydrohelicene-type compounds ill good yields. A similar photoreaction of the spiro[furan-2(3H),1'-benzocycloalkane]s afforded dihydrophenalene derivatives in moderate yields. Benzo[kl]xanthene was also formed by a similar photoreaction of spiro[furan-2(3H),9'-xanthene]. The reaction pathway was elucidated by the H-1 NMR spectrum of the reaction mixture and the alternative synthesis of the intermediate. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.08.134
• 作为产物：
  描述：

  3-acetyl-2-methyl-9b-phenyl-3aH-benzo[e]cyclohexa[1,2-b]furan 在 盐酸 作用下， 以 乙腈 为溶剂， 反应 6.0h， 以61%的产率得到1-(5-Methyl-7,8-dihydro-benzo[c]phenanthren-6-yl)-ethanone
  参考文献：
  名称：

  Photo-induced aromatic assembly of benzocycloalka[1,2-b] furan and spiro[furan-2(3H),1′-benzocycloalkane] derivatives

  摘要：

  The photo-induced benzannulation of benzocycloalka[1,2-b]furans produced hydrohelicene-type compounds ill good yields. A similar photoreaction of the spiro[furan-2(3H),1'-benzocycloalkane]s afforded dihydrophenalene derivatives in moderate yields. Benzo[kl]xanthene was also formed by a similar photoreaction of spiro[furan-2(3H),9'-xanthene]. The reaction pathway was elucidated by the H-1 NMR spectrum of the reaction mixture and the alternative synthesis of the intermediate. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.08.134

文献信息

• Photo-induced aromatic assembly of benzocycloalka[1,2-b] furan and spiro[furan-2(3H),1′-benzocycloalkane] derivatives
  作者：Reika Fujino、Shougo Kajikawa、Hiroshi Nishino

  DOI：10.1016/j.tetlet.2005.08.134

  日期：2005.10

  The photo-induced benzannulation of benzocycloalka[1,2-b]furans produced hydrohelicene-type compounds ill good yields. A similar photoreaction of the spiro[furan-2(3H),1'-benzocycloalkane]s afforded dihydrophenalene derivatives in moderate yields. Benzo[kl]xanthene was also formed by a similar photoreaction of spiro[furan-2(3H),9'-xanthene]. The reaction pathway was elucidated by the H-1 NMR spectrum of the reaction mixture and the alternative synthesis of the intermediate. (c) 2005 Elsevier Ltd. All rights reserved.