| 280784-29-4

• 分子结构分类: 有机化合物 - 碳氢化合物衍生物
• CAS: 280784-29-4
• 化学式: C₂₀H₃₈Zn
• 分子量: 343.912
• InChiKey: QFKKFCKUQVVBEP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.85
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  乙烯基环己烷 、 diethylzinc 在 二氯二茂锆 、 乙基溴化镁 作用下， 以 四氢呋喃 为溶剂， 生成
  参考文献：
  名称：

  Ethylzincation of Monosubstituted Alkenes Catalyzed by EtMgBr−Cl₂ZrCp₂ and Palladium-Catalyzed Cross Coupling of the Resultant Diisoalkylzinc Derivatives

  摘要：

  The reaction of monosubstituted alkenes with 0.5 molar equiv of Et2Zn in the presence of a catalyst generated in situ by treatment of Cl2ZrCp2 with 2 molar equiv of EtMgBr produces regioselectively the corresponding diisoalkylzincs 1, generally in high yields. Their direct cross coupling with a variety of organic halides in the same reaction vessel can be achieved in good yields with a catalytic amount of a palladium complex.

  DOI：

  10.1021/om991004j

文献信息

• Ethylzincation of Monosubstituted Alkenes Catalyzed by EtMgBr−Cl₂ZrCp₂ and Palladium-Catalyzed Cross Coupling of the Resultant Diisoalkylzinc Derivatives
  作者：Sebastien Gagneur、Jean-Luc Montchamp、Ei-ichi Negishi

  DOI：10.1021/om991004j

  日期：2000.6.1

  The reaction of monosubstituted alkenes with 0.5 molar equiv of Et2Zn in the presence of a catalyst generated in situ by treatment of Cl2ZrCp2 with 2 molar equiv of EtMgBr produces regioselectively the corresponding diisoalkylzincs 1, generally in high yields. Their direct cross coupling with a variety of organic halides in the same reaction vessel can be achieved in good yields with a catalytic amount of a palladium complex.