tert-butyl 2-diazo-3-oxo-oct-7-enoate | 928301-98-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: tert-butyl 2-diazo-3-oxo-oct-7-enoate
• 英文别名: (2E)-2-diazonio-1-[(2-methylpropan-2-yl)oxy]-1-oxoocta-2,7-dien-3-olate
• CAS: 928301-98-8
• 化学式: C₁₂H₁₈N₂O₃
• 分子量: 238.287
• InChiKey: WALQZMSIVLZKIM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  77.5
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  tert-butyl 2-diazo-3-oxo-oct-7-enoate 以 乙腈 为溶剂， 反应 5.0h， 以87%的产率得到2-(tert-butoxycarbonyl)hept-6-enoic acid
  参考文献：
  名称：

  A Tetramethoxybenzophenone as Efficient Triplet Photocatalyst for the Transformation of Diazo Compounds

  摘要：

  The aromatic ketone 2,2',4,4'-tetramethoxybenzophenone has a strong absorption band between 300 and 375 nm, and its pi,pi* triplet excited-state is selectively populated in methanol. Both facts make this aromatic ketone a versatile and efficient triplet photocatalyst for the transformation of alpha-diazo carbonyl compounds into mainly the cyclopropanation product.

  DOI：

  10.1021/jo062426n
• 作为产物：
  描述：

  tert-butyl 3-oxooct-7-enoate 在 三乙胺 、 甲烷磺酰基叠氮化物 作用下， 以 乙腈 为溶剂， 反应 3.0h， 以78%的产率得到tert-butyl 2-diazo-3-oxo-oct-7-enoate
  参考文献：
  名称：

  A Tetramethoxybenzophenone as Efficient Triplet Photocatalyst for the Transformation of Diazo Compounds

  摘要：

  The aromatic ketone 2,2',4,4'-tetramethoxybenzophenone has a strong absorption band between 300 and 375 nm, and its pi,pi* triplet excited-state is selectively populated in methanol. Both facts make this aromatic ketone a versatile and efficient triplet photocatalyst for the transformation of alpha-diazo carbonyl compounds into mainly the cyclopropanation product.

  DOI：

  10.1021/jo062426n

文献信息

• A Tetramethoxybenzophenone as Efficient Triplet Photocatalyst for the Transformation of Diazo Compounds
  作者：Lourdes Pastor-Pérez、Christine Wiebe、Julia Pérez-Prieto、Salah-Eddine Stiriba

  DOI：10.1021/jo062426n

  日期：2007.2.1

  The aromatic ketone 2,2',4,4'-tetramethoxybenzophenone has a strong absorption band between 300 and 375 nm, and its pi,pi* triplet excited-state is selectively populated in methanol. Both facts make this aromatic ketone a versatile and efficient triplet photocatalyst for the transformation of alpha-diazo carbonyl compounds into mainly the cyclopropanation product.