1-(2-ethyl-1H-imidazol-1-yl)propan-2-amine | 1248743-57-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-(2-ethyl-1H-imidazol-1-yl)propan-2-amine
• 英文别名: 1-(2-ethylimidazol-1-yl)propan-2-amine
• CAS: 1248743-57-8
• 化学式: C₈H₁₅N₃
• 分子量: 153.22
• InChiKey: UGGOWINFSCPFEX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  43.8
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• SMALL MOLECULE MENIN INHIBITORS
  申请人：THE REGENTS OF THE UNIVERSITY OF MICHIGAN

  公开号：US20210353610A1

  公开（公告）日：2021-11-18

  The present disclosure provides compounds represented by Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein R 1a , R 1b , R 1c , E, G, and Q are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I for use to treat cancer or any other disease, condition, or disorder that is responsive to inhibition of menin.