1-(di-tert-butylphosphinomethyl)-2-(di-tert-butylphosphino)benzene | 1105107-17-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(di-tert-butylphosphinomethyl)-2-(di-tert-butylphosphino)benzene
• 英文别名: o-di(tert-butyl)phosphino-benzyl-di(tert-butyl)phosphine；o-C6H4(CH2P(t-Bu)2)(P(t-Bu)2)；Ditert-butyl-[2-(ditert-butylphosphanylmethyl)phenyl]phosphane
• CAS: 1105107-17-2
• 化学式: C₂₃H₄₂P₂
• 分子量: 380.534
• InChiKey: KLABTTOCEFBDRG-UHFFFAOYSA-N

物化性质

• 沸点：
  449.4±38.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  tris(norbornene)platinum(0) 、 1-(di-tert-butylphosphinomethyl)-2-(di-tert-butylphosphino)benzene 以 甲苯 为溶剂， 反应 18.0h， 以86%的产率得到[Pt(Lb)(η2-norbornene)]
  参考文献：
  名称：

  Reversible CO exchange at platinum(0). An example of similar complex properties produced by ligands with very different stereoelectronic characteristics

  摘要：

  电子富集、体积庞大的二膦配体La和Lb支持三配位和四配位的羰基铂(0)配合物，电子贫穷的二膦配体Lf也支持这种配合物。

  DOI：

  10.1039/c4dt02303j
• 作为产物：
  描述：

  o-bromo-benzyl-di(tert-butyl)phosphine 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 、 正戊烷 为溶剂， 反应 26.0h， 生成 1-(di-tert-butylphosphinomethyl)-2-(di-tert-butylphosphino)benzene
  参考文献：
  名称：

  油酸甲酯异构化烷氧羰基化反应中的催化剂活性和选择性

  摘要：

  不对称二膦配体的合成（3 -克）与ö甲苯基骨架和叔丁基，金刚烷基，环己基和异丙基取代基的磷部分被描述（1,2-（CH 2 PR 2）（PR' 2）C 6 H 4；3 a：R = t Bu，R'= t Bu，3 b：R = t Bu，R'= Cy，3 c：R = t Bu，R'= i Pr，3 d： R = Ad，R'= t Bu，3 e：R = Ad，R'= Cy，3 f：R ＝ Cy，R′＝ Cy，3g：R ＝ Ad，R′＝ Ad）。制备了相应的二膦-Pd II二triflate配合物[（P ^ P）Pd（OTf）2 ]（5 a – g），并通过X射线晶体学对其结构进行了表征。这些新的配合物在油酸甲酯的甲氧基羰基异构化中作为催化剂的前体进行了研究，发现它们以70-80％的选择性将油酸甲酯转化为相应的线性α，ω-二酯（L）。该催化反应的产物与已知的[{1,2，（t Bu 2 PCH 2）2

  DOI：

  10.1002/chem.201301124

文献信息

• Interplay of bite angle and cone angle effects. A comparison between o-C₆H₄(CH₂PR₂)(PR′₂) and o-C₆H₄(CH₂PR₂)(CH₂PR′₂) as ligands for Pd-catalysed ethene hydromethoxycarbonylation
  作者：Tamara Fanjul、Graham Eastham、Joelle Floure、Sebastian J. K. Forrest、Mairi F. Haddow、Alex Hamilton、Paul G. Pringle、A. Guy Orpen、Mark Waugh

  DOI：10.1039/c2dt31913f

  日期：——

  determined and show that the crystallographic bite angles and cone angles are greater for L1a1a than L3a3a3a. Solution NMR studies show that the seven-membered chelate in 1a is more rigid than the six-membered chelate in 2a. Treatment of [PtCl(CH3)(cod)] with L3a–f3a–f gave [PtCl(CH3)(L3a–f3a–f)] as mixtures of 2 isomers 3a–f and 4a–f. The ratio of the products 4 : 3 ranges from 100 : 1 to 1 : 20, the precise

  制备了以下不对称二膦：o -C 6 H 4（CH 2 P t Bu 2）（PR 2）其中R ＝Pt Bu 2（L 3a 3a3a）；PCg（L 3b 3b）; PPh 2（L 3c 3c3c）; P（o -C 6 H 4 CH 3）2（L 3d 3d3d）; P（o -C 6 H 4OCH 3）2（L 3e 3e）和o -C 6 H 4（CH 2 PCg）（PCg）（L 3f 3f），其中PCg为6-phospha-2,4,8-trioxa-1,3,5， 7-四甲基金刚烷基-6-基。氢甲氧基羰基化乙烯在商业上相关的条件下，对每种配体L 3a–f 3a–f的Pd配合物进行了研究，并将结果与​​商业上使用的o -C 6 H 4（CH 2 P t Bu 2）进行了比较。2（L 1a 1a）。体积最大的配体的钯配合大号3A 3a3a，大号3B 3B和大号3F 3F是高活性的催化剂，但的钯配合大号3C
• [EN] A CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE<br/>[FR] PROCÉDÉ CONTINU DE CARBONYLATION DE L'ÉTHYLÈNE
  申请人：LUCITE INT UK LTD

  公开号：WO2011073655A1

  公开（公告）日：2011-06-23

  A continuous process for carbonylation of ethylene in a liquid phase using carbon monoxide, a co-reactant and a suitable catalyst system is described. The process comprises the steps of: (i) forming a liquid phase comprising the co-reactant and a suitable catalyst system obtainable by combining: (a) a group VIII metal/compound; (b) a ligand of general formula (I) and c) optionally, a source of anions; wherein Q1 is optionally phosphorous; (ii) forming a gaseous phase in contact with the liquid phase by providing at least an ethylene gas input feed stream and a carbon monoxide gas input feed stream wherein the ethylene:CO molar ratio entering the liquid phase from the input feed streams is greater than 2:1; (iii) reacting ethylene with carbon monoxide in the presence of the co-reactant, and of the suitable catalyst system in the liquid phase; wherein the ethylene:CO gas molar ratio in the gaseous phase is between 20:1 and 1000:1 or wherein the molar ratio of ethylene:CO in the liquid phase is greater than 10:1.

  描述了一种在液相中使用一氧化碳、共同反应剂和适当的催化剂体系对乙烯进行羰基化的连续过程。该过程包括以下步骤：(i)形成包括共同反应剂和适当催化剂体系的液相，所述催化剂体系可通过组合获得：(a) VIII族金属/化合物；(b) 一般式(I)的配体和(c) 可选地，阴离子源；其中Q1可选为磷；(ii)通过提供至少一个乙烯气体输入流和一个一氧化碳气体输入流形成与液相接触的气相，在其中从输入流中进入液相的乙烯：CO摩尔比大于2:1；(iii)在液相中的共同反应剂和适当的催化剂体系的存在下，将乙烯与一氧化碳反应；其中气相中的乙烯：CO气体摩尔比在20:1至1000:1之间，或液相中的乙烯：CO摩尔比大于10:1。
• CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE
  申请人：Lucite International UK Limited

  公开号：US20150099896A1

  公开（公告）日：2015-04-09

  A continuous process for the production of an alkyl ester product is described. The process includes the steps of carbonylating ethylene with carbon monoxide in the presence of C1-6 alkanol co-reactant to form the alkyl ester product. The carbonylation takes place in the presence of a catalyst system that includes (a) a bidentate ligand, (b) a catalytic metal selected from a group 8, 9 or 10 metal or a compound thereof, and (c) a sulphonic acid capable of forming an acid alkyl ester with the C1-6 alkanol. The process includes the step of separating the alkyl ester product from a carbonylated crude product stream by treatment effective to vaporizing the alkyl ester product in a single stage flash distillation column and providing a purified alkyl ester product stream separated from the bidentate ligand and catalytic metal.

  描述了一种生产烷基酯产品的连续过程。该过程包括以下步骤：在C1-6烷醇共反应剂的存在下，将乙烯与一氧化碳进行羰基化反应，形成烷基酯产品。羰基化反应发生在包括（a）双齿配体、（b）选择自第8、9或10族金属或其化合物的催化金属和（c）能够与C1-6烷醇形成酸性烷基酯的磺酸的催化剂系统存在下。该过程包括将烷基酯产品从羰基化粗产品流中分离出来的步骤，通过处理有效地在单级闪蒸塔中蒸发烷基酯产品，并提供从双齿配体和催化金属分离出来的纯化的烷基酯产品流。
• POLYMERS MADE OF RENEWABLE RESOURCES
  申请人：Mecking Stefan

  公开号：US20130030075A1

  公开（公告）日：2013-01-31

  Polycondensates with long-chain linear methylene sequences, their production, a method for producing linear odd-numbered C >20 α,ω-dicarboxylic acids and derivatives thereof and applications of the polycondensates are described.

  本文描述了具有长链线性亚甲基序列的聚缩酸酯、它们的生产方法、一种生产线性奇数碳数C>20α,ω-二羧酸及其衍生物的方法以及聚缩酸酯的应用。
• PROCESS FOR THE CARBONYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND AND A CATALYST SYSTEM
  申请人：Eastham Graham Ronald

  公开号：US20100197958A1

  公开（公告）日：2010-08-05

  A process for the carbonylation of an ethylenically unsaturated compound comprising the step of reacting said compound with carbon monoxide in the presence of a co-5 reactant having a mobile hydrogen atom and a catalyst system is described. The catalyst system is obtainable by combining: (a) a metal of Group 8, 9 or 10 or a suitable compound thereof; (b) a ligand of general formula (I): and c) optionally, a source of anions. The invention is characterised in that the catalyst system includes an enhancer compound comprising an aromatic ring or ring system substituted by at least one hydroxyl group wherein the hydroxyl group pKa at 25° C. is greater than 3.0 and less than 9.1, the said enhancer compound excluding 3-quinolinol. Catalyst systems for use with the enhancer compound are described as are a method of increasing the efficacy of a catalyst system for the carbonylation of ethylenically unsaturated compounds and a method of increasing the rate of carbonylation of an ethylenically unsaturated compound comprising the step of adding such a compound to the reaction.

  本发明涉及一种用于羰基化具有乙烯基不饱和化合物的方法，包括在具有移动氢原子的共反应剂和催化剂体系存在下，将该化合物与一氧化碳反应的步骤。所述催化剂体系可通过组合以下成分获得：（a）第8、9或10族金属或其适当化合物；（b）一般式（I）的配体；以及（c）可选地，阴离子源。本发明的特点在于，催化剂体系包括增强剂化合物，该化合物包括由至少一个羟基取代的芳香环或环系，其中该羟基在25℃时的pKa大于3.0且小于9.1，所述增强剂化合物不包括3-喹啉酚。本发明还描述了用于增强剂化合物的催化剂体系，以及增加用于羰基化乙烯基不饱和化合物的催化剂体系效力和增加羰基化乙烯基不饱和化合物的反应速率的方法。