(E)-1-acetyl-4-(phenyloxy)-2-butene | 111155-52-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (E)-1-acetyl-4-(phenyloxy)-2-butene
• 英文别名: (E)-1-acetoxy-4-phenoxy-2-butene；[(E)-4-phenoxybut-2-enyl] acetate
• CAS: 111155-52-3
• 化学式: C₁₂H₁₄O₃
• 分子量: 206.241
• InChiKey: SQSKBDUPUKVULB-AATRIKPKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (E)-1-acetyl-4-(phenyloxy)-2-butene 、 alkaline earth salt of/the/ methylsulfuric acid 生成 2-(乙烯基)己基乙酸酯
  参考文献：
  名称：

  Baeckval, Jan-E, Bulletin de la Societe Chimique de France, 1987, # 5, p. 665 - 670

  摘要：

  DOI：
• 作为产物：
  描述：

  (E)-1-chloro-4-acetoxybut-2-ene 、 苯酚 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 以75%的产率得到(E)-1-acetyl-4-(phenyloxy)-2-butene
  参考文献：
  名称：

  Baeckval, Jan-E, Bulletin de la Societe Chimique de France, 1987, # 5, p. 665 - 670

  摘要：

  DOI：

文献信息

• Method for producing allyl compound, and ether or ester compound produced thereby
  申请人：MITSUBISHI CHEMICAL CORPORATION

  公开号：US20040147757A1

  公开（公告）日：2004-07-29

  A method for producing an allyl compound having a compositional formula different from that of an allyl starting material compound, which comprises reacting the allyl starting material compound with an oxygen nucleophilic agent in the presence of a catalyst containing at least one transition metal compound containing a transition metal selected from the group consisting of transition metals belonging to Group 8 to Group 10 of the Periodic Table and a multidentate phosphite compound.

  一种生产具有与烯丙基起始物质化合物不同的组成式的烯丙基化合物的方法，包括在存在至少一种含有从周期表第8组到第10组的过渡金属属于的过渡金属的过渡金属化合物和多齿膦酸酯化合物的催化剂的情况下，将烯丙基起始物质化合物与氧亲核试剂反应。
• Asymmetric Induction in the Arenethiolatocopper(I)-Catalyzed Substitution Reaction of Grignard Reagents with Allylic Substrates
  作者：Gerrit J. Meuzelaar、A.Sofia E. Karlström、Mayra van Klaveren、Eva S.M. Persson、Amaya del Villar、Gerard van Koten、Jan-E. Bäckvall

  DOI：10.1016/s0040-4020(00)00145-9

  日期：2000.4

  experimental parameters on the regio- and enantioselectivity in the γ-selective substitution reaction of Grignard reagents RMgX with acyclic allylic acetates catalyzed by the arenethiolatocopper(I) complex (S)-1 was studied. When more bulky arenethiolatocopper(I) complexes than (S)-1 were employed in a reaction of allylic acetate 3 with n-BuMgI, the enantioselectivities observed for the γ-product were

  研究了一些实验参数对苯丙氨酸铜（I ）- （S）-1催化的格氏试剂RMgX与无环烯丙基乙酸酯γ选择性取代反应中区域和对映选择性的影响。当在乙酸烯丙酯3与n- BuMgI的反应中使用比（S）-1多的大体积的槟榔铜（I）络合物时，观察到的γ-产物的对映选择性较低。用原位制备的槟榔铜（I）催化剂，在用乙酸2取代反应中研究了几种格氏试剂。与n相比-BuMgI，更笨重的格氏试剂在γ-产物的形成中没有提高对映选择性。
• “Palladium complexes-KF / alumina” catalysed exchange of allylic groups of esters with phenol
  作者：J. Muzart、J.-P. Genêt、A. Denis

  DOI：10.1016/0022-328x(87)80136-5

  日期：1987.5

  In the presence of KF / alumina and catalytic amounts of palladium complexes, phenol reacts with allylic esters under mild conditions to give the corresponding allyl phenyl ethers.

  在KF /氧化铝和催化量的钯配合物存在下，苯酚在温和条件下与烯丙基酯反应，生成相应的烯丙基苯基醚。
• A dual regiocontrol in the copper-catalysed Grignard reaction with primary allylic acetates
  作者：Jan-E. Bäckvall、Michael Sellén

  DOI：10.1039/c39870000827

  日期：——

  The reaction of primary allylic acetates with Grignard reagents in the presence of catalytic amounts of Li2CuCl4 can be regiochemically controlled to give either α- or γ-substitution of the allylic acetoxy group.

  在催化量的Li 2 CuCl 4的存在下，伯烯丙基乙酸酯与格利雅试剂的反应可以被区域化学控制以得到烯丙基乙酰氧基的α-或γ-取代。
• Method for producing allyl compound, and allyl compound produced thereby
  申请人：Takai Masaki

  公开号：US20050075518A1

  公开（公告）日：2005-04-07

  A method for producing an allyl compound having a compositional formula different from that of an allyl starting material compound, which comprises reacting the allyl starting material compound with a nucleophilic agent in the presence of a catalyst containing at least one transitional metal compound containing a transition metal selected from the group consisting of transition metals belonging to Group 8 to Group 10 of the Periodic Table and at least one bidentate coordinated phosphite compound selected from the group consisting of compounds having structures of the following formulae (I) to (III): wherein A 1 to A 3 are respectively independently a diarylene group having a branched alkyl group at the ortho-position, R 1 to R 6 are respectively independently an alkyl group which may have a substituent or an aryl group which may have a substituent (including a heterocyclic compound forming an aromatic 6π electron cloud on the upper and lower sides of the ring, hereinafter the same), and Z 1 to Z 3 are respectively independently an alkylene group which may have a substituent, an arylene group which may have a substituent, an alkylene-arylene group which may have a substituent or a diarylene group which may have a substituent.

  一种制备具有不同于烯丙基起始材料化合物的组成式的烯丙基化合物的方法，包括在催化剂的存在下，将烯丙基起始材料化合物与亲核试剂反应，所述催化剂包含至少一种过渡金属化合物，所述过渡金属选自周期表8到10组的过渡金属，并且至少一种双齿配位膦酸酯化合物，所述化合物具有以下式(I)到(III)中的结构，其中A1到A3分别独立地是具有支链烷基的二芳基基团，R1到R6分别独立地是可以具有取代基的烷基基团或可以具有取代基的芳基基团（包括在环上形成芳香6π电子云的杂环化合物，在此以后相同），Z1到Z3分别独立地是可以具有取代基的烷基，可以具有取代基的芳基，可以具有取代基的烷基-芳基基团或可以具有取代基的二芳基基团。