3-(1H-pyrazol-1-yl)butan-2-amine | 956805-00-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3-(1H-pyrazol-1-yl)butan-2-amine
• 英文别名: 3-pyrazol-1-ylbutan-2-amine
• CAS: 956805-00-8
• 化学式: C₇H₁₃N₃
• mdl: MFCD09261650
• 分子量: 139.2
• InChiKey: JUJSJFUYRXZKCK-UHFFFAOYSA-N

物化性质

• 沸点：
  218.0±23.0 °C(Predicted)
• 密度：
  1.09±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.571
• 拓扑面积：
  43.8
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• 1H-pyrazolyl derivative compounds, for use in diseases associated with the 5-ht2c receptor
  申请人：Ladouceur H. Gaetan

  公开号：US20050119246A1

  公开（公告）日：2005-06-02

  Disclosed are pyrazolyl derivative compounds or purified stereoisomers or stereoisomer mixtures of said compounds and their salts or prodrug forms thereof which have structural formula (I) or (II): wherein the variables R, R 1 , R 2 , R 5 and R 6 are as defined in the specification. The compounds are useful for the treatment or prevention of diseases and/or behaviors involving the 5-HT 2C receptor.

  本发明涉及吡唑基衍生物化合物或其纯化的立体异构体或立体异构体混合物及其盐或前药形式，其具有结构式（I）或（II）：其中变量R、R1、R2、R5和R6如规范中所定义。该化合物可用于治疗或预防涉及5-HT2C受体的疾病和/或行为。
• PYRAZOLE DERIVATIVES FOR USE IN DISEASES ASSOCIATED WITH THE 5-HT2C RECEPTOR
  申请人：Bayer Corporation

  公开号：EP1465871A1

  公开（公告）日：2004-10-13
• [EN] 1H-PYRAZOLYL DERIVATIVE COMPOUNDS, FOR USE IN DISEASES ASSOCIATED WITH THE 5-HT2C RECEPTOR<br/>[FR] COMPOSES DERIVES DE 1H-PYROZOLYLE, POUVANT ETRE UTILISES DANS LES MALADIES ASSOCIEES AU RECEPTEUR 5-HT2C
  申请人：BAYER AG

  公开号：WO2003057673A1

  公开（公告）日：2003-07-17

  Disclosed are pyrazolyl derivative compounds or purified stereoisomers or stereoisomer mixtures of said compounds and their salts or prodrug forms thereof which have structural formula (I) or (II): wherein the variables R, R1, R2, R5 and R6 are as defined in the specification. The compounds are useful for the treatment or prevention of diseases and/or behaviors involving the 5-HT2C receptor .