2-chloro-N-[(S)-1-hydroxy-3,3-dimethylbutan-2-yl]propanamide | 1240349-83-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-chloro-N-[(S)-1-hydroxy-3,3-dimethylbutan-2-yl]propanamide
• CAS: 1240349-83-0
• 化学式: C₉H₁₈ClNO₂
• 分子量: 207.7
• InChiKey: XVJKYAVDGFNFKY-COBSHVIPSA-N

反应信息

• 作为反应物：
  描述：

  2-chloro-N-[(S)-1-hydroxy-3,3-dimethylbutan-2-yl]propanamide 、 苯硫酚 在 sodium ethanolate 作用下， 以 乙醇 为溶剂， 反应 0.33h， 生成 N-[(S)-1-hydroxy-3,3-dimethylbutan-2-yl-2-(phenylthio)]propanamide 、 N-[(S)-1-hydroxy-3,3-dimethylbutan-2-yl-2-(phenylthio)]propanamide
  参考文献：
  名称：

  Diastereoselective sulfur oxidation of 2-thio-3-chloroacrylamides

  摘要：

  Diastereoselective sulfur oxidation in 2-thio-3-chloroacrylamides is described A range of chiral amine auxiliaries was incorporated in the beta-chloroacrylamide, and the efficiency with which the stereochemistry was relayed to the sulfur centre during sulfoxidation was investigated. Diastereomeric ratios of up to 3 3 1 were achieved. (C) 2010 Elsevier Ltd. All rights reserved

  DOI：

  10.1016/j.tetasy.2010.05.004