N,N'-二烯丙基琥珀酰胺 | 45125-63-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: N,N'-二烯丙基琥珀酰胺
• 英文名称: N,N'-diallyl-succinamide
• 英文别名: Bernsteinsaeure-bis-allylamid；N,N'-Diallyl-succinamid；N,N'-bis(prop-2-enyl)butanediamide
• CAS: 45125-63-1
• 化学式: C₁₀H₁₆N₂O₂
• 分子量: 196.249
• InChiKey: ZIIYHBZHCMUKFD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  丁二酸酐 、 丙烯胺 在 苯 作用下， 生成 N-allylsuccinimide 、 N,N'-二烯丙基琥珀酰胺
  参考文献：
  名称：

  Szekeres, Gazzetta Chimica Italiana, 1949, vol. 79, p. 56,59

  摘要：

  DOI：

文献信息

• [DE] JOD-PHENYLSUBSTITUIERTE CYCLISCHE KETOENOLE<br/>[EN] IODINE-PHENYL-SUBSTITUTED CYCLIC CETOENOLS<br/>[FR] CETOENOLS CYCLIQUES A SUBSTITUTION IODE-PHENOL
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2006029799A1

  公开（公告）日：2006-03-23

  Die Erfindung betrift neue Jod-phenylsubstituierte cyclische Ketenole der Formel (I) in welcher CKE, J, X und Y die oben angegebenen Bedeutungen haben, mehrere Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel und/oder Herbizide, sowie selektiv herbizide Mittel, die Jod-phenylsubstituierte cyclische Ketonole der Formel (I) einerseits und zumindest eine die Kulturpflanzenverträglichkeit verbessernde Verbindung andererseits enthalten.

  这项发明涉及新的Jod-苯基取代的环状酮烯化合物的公式(I)，其中CKE，J，X和Y具有上述给定的含义，以及它们的制备方法和中间体，以及它们作为杀虫剂和/或除草剂的用途，以及选择性除草剂，其中一方面含有公式(I)中的Jod-苯基取代的环状酮烯化合物，另一方面至少包含一种改善对农作物耐受性的化合物。
• [EN] BISUREA GELLING AGENTS AND COMPOSITIONS<br/>[FR] AGENTS GÉLIFIANTS DE TYPE BIURÉE ET COMPOSITIONS ASSOCIÉES
  申请人：MILLIKEN & CO

  公开号：WO2013033300A1

  公开（公告）日：2013-03-07

  Bisurea gelling agents that impart a number of unexpected benefits within various gelled formulations and exhibit great versatility in terms of gelling capabilities for many types of solvents are provided. Such gelling agents should include pendant groups, such as sterically hindering alkyl groups attached to polyoxyalkylenated moieties that allow the gelling agent to be compatible with the target liquid system at elevated temperatures, while controlling and/or limiting the network formation and strength during the cooling cycle. The result is that a reliable, hard gel is formed that does not crash out of solution easily and that does not exhibit unwanted cracking or precipitating out within the final formulation. Alternatively, novel gelling agents having two urea groups but that are asymmetrical in configuration have been produced in order to provide the same control in temperature, compatibility, and efficiency. Final gelled formulations, such as antiperspirant sticks and other like consumer items, are provided as well within this invention.

  本文提供了一种Bisurea凝胶剂，它在各种凝胶配方中带来了许多意想不到的好处，并且在凝胶能力方面表现出极大的多样性，适用于许多类型的溶剂。这种凝胶剂应包括挂链基团，例如附加到聚氧烷基化物上的空间阻碍烷基基团，使凝胶剂在升高的温度下与目标液体系统兼容，同时在冷却周期中控制和/或限制网络形成和强度。结果是形成了可靠的坚硬凝胶，不易从溶液中崩解，不会在最终配方中出现不必要的开裂或沉淀。另外，为了提供相同的温度、兼容性和效率控制，还制备了具有两个脲基但配置不对称的新型凝胶剂。本发明还提供了最终的凝胶配方，例如止汗膏和其他类似的消费品。
• Lactams substituted by cyclic succinates as inhibitors of a beta protein production
  申请人：——

  公开号：US20020137737A1

  公开（公告）日：2002-09-26

  This invention relates to novel lactams having the Formula (I): 1 to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifically, inhibit the production of A&bgr;-peptide, thereby acting to prevent the formation of neurological deposits of amyloid protein. More particularly, the present invention relates to the treatment of neurological disorders related to &bgr;-amyloid production such as Alzheimer's disease and Down's Syndrome.

  这项发明涉及具有式(I)的新型内内酰胺，以及它们的药物组合物和使用方法。这些新型化合物抑制淀粉样前体蛋白的加工，更具体地说，抑制Aβ-肽的产生，从而防止淀粉样蛋白的神经沉积形成。更具体地说，本发明涉及治疗与β-淀粉样蛋白产生相关的神经系统疾病，如阿尔茨海默病和唐氏综合征。
• Lactams substituted by cyclic succinates as inhibitors of Abeta protein production
  申请人：Olson E. Richard

  公开号：US20050261274A1

  公开（公告）日：2005-11-24

  This invention relates to novel lactams having the Formula (I): to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifically, inhibit the production of Aβ-peptide, thereby acting to prevent the formation of neurological deposits of amyloid protein. More particularly, the present invention relates to the treatment of neurological disorders related to β-amyloid production such as Alzheimer's disease and Down's Syndrome.

  本发明涉及具有公式（I）的新型内酰胺，其制药组成物和使用方法。这些新化合物抑制淀粉样前体蛋白的处理，更具体地抑制Aβ-肽的产生，从而防止神经元中淀粉样蛋白的沉积形成。更具体地，本发明涉及与β-淀粉样蛋白产生相关的神经系统疾病的治疗，如阿尔茨海默病和唐氏综合症。
• Lactams substituted by cyclic succinates as inhibitors of A-beta protein production
  申请人：——

  公开号：US20030119815A1

  公开（公告）日：2003-06-26

  This invention relates to novel lactams having the Formula (I): 1 to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifically, inhibit the production of A&bgr;-peptide, thereby acting to prevent the formation of neurological deposits of amyloid protein. More particularly, the present invention relates to the treatment of neurological disorders related to &bgr;-amyloid production such as Alzheimer's disease and Down's Syndrome.

  本发明涉及具有公式(I)的新型内酰胺，以及它们的制药组合物和使用方法。这些新化合物抑制淀粉样前体蛋白的处理，更具体地抑制Aβ-肽的产生，从而防止神经元中出现淀粉样蛋白质的沉积。更具体地说，本发明涉及治疗与β-淀粉样蛋白产生相关的神经系统疾病，如阿尔茨海默病和唐氏综合症。