2-(4-tert-butylphenyl)-6-methoxybenzo[b]furan | 1429209-48-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 2-芳基苯并呋喃类黄酮
• 英文名称: 2-(4-tert-butylphenyl)-6-methoxybenzo[b]furan
• 英文别名: 2-(4-tert-butylphenyl)-6-methoxybenzofuran；2-(4-Tert-butylphenyl)-6-methoxy-1-benzofuran；2-(4-tert-butylphenyl)-6-methoxy-1-benzofuran
• CAS: 1429209-48-2
• 化学式: C₁₉H₂₀O₂
• 分子量: 280.367
• InChiKey: REUOBTZNRXJAQE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  22.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(4-tert-butylphenyl)-6-methoxybenzo[b]furan 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 以98%的产率得到3-bromo-2-(4-(tert-butyl)phenyl)-6-methoxybenzofuran
  参考文献：
  名称：

  US2014/256936

  摘要：

  公开号：
• 作为产物：
  描述：

  3-甲氧基苯酚 在 tris-(dibenzylideneacetone)dipalladium(0) 、 caesium carbonate 、 cesium fluoride 、 双(2-二苯基磷苯基)醚 、 sodium hydroxide 作用下， 以 1,4-二氧六环 、 二甲基亚砜 为溶剂， 反应 48.0h， 生成 2-(4-tert-butylphenyl)-6-methoxybenzo[b]furan
  参考文献：
  名称：

  US2014/256936

  摘要：

  公开号：

文献信息

• Palladium-Catalyzed Addition of Potassium Aryltrifluoroborates to Aliphatic Nitriles: Synthesis of Alkyl Aryl Ketones, Diketone Compounds, and 2-Arylbenzo[<i>b</i>]furans
  作者：Xingyong Wang、Miaochang Liu、Long Xu、Qingzong Wang、Jiuxi Chen、Jinchang Ding、Huayue Wu

  DOI：10.1021/jo400433m

  日期：2013.6.7

  developed, leading to a wide range of alkyl aryl ketones with moderate to excellent yields. Moreover, several dinitriles (e.g., malononitrile, glutaronitrile, and adiponitrile) were applicable to this process for the construction of 1,3-, 1,5-, or 1,6-dicarbonyl compounds. The scope of the developed approach is successfully explored toward the one-step synthesis of 2-arylbenzo[b]furans via sequential

  已经开发了钯催化的芳基三氟硼酸钾加成到脂肪族腈中的方法，从而产生了范围广泛的烷基芳基酮，并具有中等至极好的收率。此外，几种二腈（例如丙二腈，戊二腈和己二腈）适用于该方法，用于构建1,3-，1,5-或1,6-二羰基化合物。通过顺序加成和分子内环化反应，一步一步合成2-芳基苯并[ b ]呋喃已成功探索了所开发方法的范围。该方法学接受了广泛的底物，并适用于文库合成。
• DIARYLETHENE COMPOUNDS AND USES THEREOF
  申请人：SWITCH MATERIALS, INC.

  公开号：US20160083398A1

  公开（公告）日：2016-03-24

  A compound according to Formula IA and IB, reversibly convertible under photochromic and electrochromic conditions between a ring-open isomer A and a ring-closed isomer B is provided. For substitutent groups, Z is N, O or S; each R 1 is independently selected from the group consisting of H, or halo; each R 2 is independently selected from the group consisting of H, halo, a polymer backbone, alkyl or aryl; or, when both R 2 together form —CH═CH— and form part of a polymer backbone; each R 3 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl; each R 4 is aryl; and each R 5 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl.

  本发明提供了一种按照式IA和IB的化合物，在光致变色和电致变色条件下，可在环开放异构体A和环闭合异构体B之间可逆地转化。对于取代基，Z为N、O或S；每个R1独立地选自H或卤素；每个R2独立地选自H、卤素、聚合物骨架、烷基或芳基；或者，当两个R2一起形成-CH═CH-并形成聚合物骨架的一部分时；每个R3独立地选自H、卤素、烷基、烷氧基、硫代烷基或芳基；每个R4为芳基；每个R5独立地选自H、卤素、烷基、烷氧基、硫代烷基或芳基。
• Diarylethene compounds and uses thereof
  申请人：SWITCH MATERIALS, INC.

  公开号：US10072023B2

  公开（公告）日：2018-09-11

  A compound according to Formula IA and IB, reversibly convertible under photochromic and electrochromic conditions between a ring-open isomer A and a ring-closed isomer B is provided. For substitutent groups, Z is N, O or S; each R1 is independently selected from the group consisting of H, or halo; each R2 is independently selected from the group consisting of H, halo, a polymer backbone, alkyl or aryl; or, when both R2 together form —CH═CH— and form part of a polymer backbone; each R3 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl; each R4 is aryl; and each R5 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl.

  提供了一种根据式 IA 和 IB 的化合物，该化合物在光致变色和电致变色条件下可在开环异构体 A 和闭环异构体 B 之间进行可逆转换。对于取代基，Z 是 N、O 或 S；每个 R1 独立地选自 H 或卤代；每个 R2 独立地选自 H、卤代、聚合物骨架、烷基或芳基；或者，当两个 R2 一起形成 -CH═CH- 并构成聚合物骨架的一部分时；每个 R3 独立地选自由 H、卤素、烷基、烷氧基、硫代烷基或芳基组成的组；每个 R4 是芳基；每个 R5 独立地选自由 H、卤素、烷基、烷氧基、硫代烷基或芳基组成的组。
• US20140256936A1
  申请人：——

  公开号：US20140256936A1

  公开（公告）日：2014-09-11
• PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS
  申请人：SWITCH MATERIALS, INC.

  公开号：US20180339995A1

  公开（公告）日：2018-11-29

  A compound according to Formula IA and IB, reversibly convertible under photochromic and electrochromic conditions between a ring-open isomer A and a ring-closed isomer B is provided. For substitutent groups, Z is N, O or S; each R 1 is independently selected from the group consisting of H, or halo; each R 2 is independently selected from the group consisting of H, halo, a polymer backbone, alkyl or aryl; or, when both R 2 together form —CH═CH— and form part of a polymer backbone; each R 3 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl; each R 4 is aryl; and each R 5 is independently selected from the group consisting of H, halo, alkyl, alkoxy, thioalkyl or aryl.