N-trans-feruloyltyramine diacetate | 66648-46-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: N-trans-feruloyltyramine diacetate
• 英文别名: diacetyl N-trans-feruloyl tyramine；(E)-N-feruloyltyramine diacetate；[4-[2-[[(E)-3-(4-acetyloxy-3-methoxyphenyl)prop-2-enoyl]amino]ethyl]phenyl] acetate
• CAS: 66648-46-2
• 化学式: C₂₂H₂₃NO₆
• 分子量: 397.428
• InChiKey: TWZYHKRHASAOIY-YRNVUSSQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  29
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  90.9
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  acetyl ferulic acid 在 吡啶 、 氢氧化钾 、 氯化亚砜 作用下， 以 四氢呋喃 、 甲醇 、 苯 为溶剂， 反应 8.0h， 生成 N-trans-feruloyltyramine diacetate
  参考文献：
  名称：

  Nakatani, Nobuji; Inatani, Reiko; Fuwa, Hidetsugu, Agricultural and Biological Chemistry, 1980, vol. 44, # 12, p. 2831 - 2836

  摘要：

  DOI：

文献信息

• Bioactive Constitutents from the Stems of<i>Annona montana</i>
  作者：Yang-Chang Wu、Gwo-Yuan Chang、Feng-Nien Ko、Che-Ming Teng

  DOI：10.1055/s-2006-958035

  日期：1995.4

  Three structurally related acid amides, N-trans-feruloyltyramine (1), N-p-coumaroyltyramine (2), and N-trans-caffeoyltyramine (3), one lignan, (-)-syringaresinol (4), one aromatic aldehyde, syringaldehyde (5), and two steroids, β-sitosterol and β-sitosterol-β-D-glucoside were isolated from the stem parts of Annona montana (Annonaceae). N-trans-Caffeoyltyramine (3) is a new natural compound. These compounds and their acetate derivatives were subjected to the antiplatelet aggregation and cytotoxicity bioassay where some of them showed significant activities.

  从茎干中分离出三种结构相关的酸酰胺，N-反式阿魏酰酪胺(1)、N-对香豆酰酪胺(2)和 N-反式咖啡酰酪胺(3)，一种木质素，(-)-紫苏烯醇(4)、从 Annona montana（芒柄花科）的茎干部分分离出一种芳香醛--丁香醛（5）和两种类固醇--δ-谷甾醇和δ-谷甾醇-δ-D-葡萄糖苷。N-trans-Caffeoyltyramine (3) 是一种新的天然化合物。对这些化合物及其醋酸衍生物进行了抗血小板聚集和细胞毒性生物测定，其中一些化合物显示出显著的活性。
• Neolignans and alkaloids from Piper argyrophylum
  作者：Sanjay K. Singh、Prasad K. Ashok、Carl E. Olsen、Amitabh Jha、Subhash C. Jain、Virinder S. Parmar、Jesper Wenge

  DOI：10.1016/s0031-9422(96)00502-x

  日期：1996.12

  Twenty-three compounds, a novel neolignan nine known neolignans and 13 known alkaloids, were isolated from a methanol extract of stems of Piper argyrophylum. The structure of the new neolignan, 4-(2-piperonyl-2-hydroxy-1-methylethyl-2,5-dimethoxy-2-(2-propenyl)-3,5-cyclohexadien-1-one, was elucidated on the basis of its spectral data, whereas the known neolignans and alkaloids were identified by comparsion

  二十三种化合物，一种新型的新木脂素，九种已知的新木脂素和 13 种已知的生物碱，是从 Piper argyrophylum 茎的甲醇提取物中分离出来的。新木脂素 4-(2-piperonyl-2-羟基-1-甲基乙基-2,5-二甲氧基-2-(2-丙烯基)-3,5-环己二烯-1-one)的结构在其光谱数据为基础，而已知的新木脂素和生物碱是通过将它们的光谱数据与先前报道的光谱数据进行比较来鉴定的。所有化合物都是来自 P. argyrophylum 的新化合物。
• Studies on the constituents of the stems of Tinospora tuberculata Beumee. I. N-trans- and N-cis-feruloyl tyramine, and a new phenolic glucoside, tinotuberide.
  作者：NAOMICHI FUKUDA、MICHIKO YONEMITSU、TAKEATSU KIMURA

  DOI：10.1248/cpb.31.156

  日期：——

  From the dried stems of Tinospora tuberculata BEUMEE (Menispermaceae), N-transferuloyl tyramine (1), N-cis-feruloyl tyramine (2), and a new phenolic glucoside, tinotuberide (6), were isolated. The structure of 6 was elucidated as 3-(4'-β-D-glucopyranosyloxy-3', 5'-dimethoxyphenylmethoxy)-2-trans-propen-1-ol.

  从贝母（Menispermaceae）的干燥茎中分离出N-转移尿酰酪胺（1）、N-顺式阿魏酰酪胺（2）和一种新的酚糖苷——贝母苷（6）。贝母苷（6）的结构被阐明为3-(4'-β-D-吡喃葡萄糖基氧基-3', 5'-二甲氧基苯甲氧基)-2-反式-丙烯-1-醇。
• Yoshihara, Teruhiko; Yamaguchi, Katsuyoshi; Takamatsu, Seiji, Agricultural and Biological Chemistry, 1981, vol. 45, # 11, p. 2593 - 2598
  作者：Yoshihara, Teruhiko、Yamaguchi, Katsuyoshi、Takamatsu, Seiji、Sakamura, Sadao

  DOI：——

  日期：——
• ZAPESOCHNAYA, G. G.;KURKIN, V. A.;PERVYX, L. N., XIMIYA PRIROD. SOED.,(1990) N, S. 694-695
  作者：ZAPESOCHNAYA, G. G.、KURKIN, V. A.、PERVYX, L. N.

  DOI：——

  日期：——