| 465532-77-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• CAS: 465532-77-8
• 化学式: C₁₇H₂₄O₆
• 分子量: 324.374
• InChiKey: YEZQWLATCWFOLA-HMDCTGQHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.01
• 重原子数：
  23.0
• 可旋转键数：
  7.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  99.38
• 氢给体数：
  4.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  在 palladium on activated charcoal 氢气 作用下， 以 甲醇 为溶剂， 生成 (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-(5-phenylpentoxy)oxane-3,4,5-triol
  参考文献：
  名称：

  Rapid Preparation of Glycolipid Libraries by Cross Metathesis

  摘要：

  A new strategy for the synthesis of a well-defined glycolipid library is presented. A highly selective cross metathesis reaction is used to diversify the lipid moiety of anomerically pure alpha- or beta-glycosides, and subsequent functionalization of the double bond allows further expansion of the diversity. These glycolipids are being investigated for their effect on the immune system, especially the CD1-mediated T-cell activation.

  DOI：

  10.1002/1615-4169(200208)344:6/7<622::aid-adsc622>3.0.co;2-w
• 作为产物：
  描述：

  在 sodium methylate 作用下， 以 甲醇 为溶剂， 反应 3.0h， 生成
  参考文献：
  名称：

  Rapid Preparation of Glycolipid Libraries by Cross Metathesis

  摘要：

  A new strategy for the synthesis of a well-defined glycolipid library is presented. A highly selective cross metathesis reaction is used to diversify the lipid moiety of anomerically pure alpha- or beta-glycosides, and subsequent functionalization of the double bond allows further expansion of the diversity. These glycolipids are being investigated for their effect on the immune system, especially the CD1-mediated T-cell activation.

  DOI：

  10.1002/1615-4169(200208)344:6/7<622::aid-adsc622>3.0.co;2-w