(R,E)-3-((3,3-dimethyloxiran-2-yl)methoxy)but-2-en-1-ol | 1304692-07-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧戊环
• 英文名称: (R,E)-3-((3,3-dimethyloxiran-2-yl)methoxy)but-2-en-1-ol
• CAS: 1304692-07-6
• 化学式: C₉H₁₆O₃
• 分子量: 172.224
• InChiKey: WCQQFZBIMYVXLB-RXLGXGPVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.08
• 重原子数：
  12.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  41.99
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  (R,E)-3-((3,3-dimethyloxiran-2-yl)methoxy)but-2-en-1-ol 在 二异丁基氢化铝 、 三甲基膦 作用下， 以 四氢呋喃 、 water-d2 、 乙醚 、 二氯甲烷 、 氘代甲醇 、 Petroleum ether 为溶剂， 反应 216.0h， 生成
  参考文献：
  名称：

  Oxygen-containing analogues of juvenile hormone III

  摘要：

  Juvenile hormone III (JH-III) controls several aspects of insect development, and analogues of JH-III are widely used as insect control agents. Recent reports suggest that these compounds may also perturb the normal development of crustaceans, and perhaps other aquatic species. In an attempt to prepare more highly degradable (and thus less environmentally persistent) mimics of JH-III, we prepared a series of analogues incorporating vinyl ether functionality. The stability of these compounds in water or warm, moist air was evaluated, revealing two distinct decomposition pathways. Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.01.103
• 作为产物：
  描述：

  异戊烯醇 在 titanium(IV) isopropylate 、 过氧化氢异丙苯 、 二异丁基氢化铝 、 三甲基膦 作用下， 以 四氢呋喃 、 乙醚 、 二氯甲烷 、 Petroleum ether 为溶剂， 反应 24.0h， 生成 (R,E)-3-((3,3-dimethyloxiran-2-yl)methoxy)but-2-en-1-ol
  参考文献：
  名称：

  Oxygen-containing analogues of juvenile hormone III

  摘要：

  Juvenile hormone III (JH-III) controls several aspects of insect development, and analogues of JH-III are widely used as insect control agents. Recent reports suggest that these compounds may also perturb the normal development of crustaceans, and perhaps other aquatic species. In an attempt to prepare more highly degradable (and thus less environmentally persistent) mimics of JH-III, we prepared a series of analogues incorporating vinyl ether functionality. The stability of these compounds in water or warm, moist air was evaluated, revealing two distinct decomposition pathways. Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.01.103