2-isopropyl-2,3-dimethyl-N-(1-(furan-2-yl)ethyl)butanamide | 1254731-38-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-isopropyl-2,3-dimethyl-N-(1-(furan-2-yl)ethyl)butanamide
• 英文别名: N-[1-(furan-2-yl)ethyl]-2,3-dimethyl-2-propan-2-ylbutanamide
• CAS: 1254731-38-8
• 化学式: C₁₅H₂₅NO₂
• 分子量: 251.369
• InChiKey: JWTQXQKCTSWDMV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  42.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  [1,2,4]三唑-1-基乙酸 、 2,3-二甲基-2-异丙基丁酰氯 在 吡啶 、 硫酸 、 氯化亚砜 作用下， 以 四氢呋喃 为溶剂， 反应 16.0h， 生成 2-isopropyl-2,3-dimethyl-N-(1-(furan-2-yl)ethyl)butanamide
  参考文献：
  名称：

  Organic Compounds Having Cooling Properties

  摘要：

  提供的化合物为公式(I)，其中m为0、1或2；RI为单环或双环杂环环系统，包括从氮、硫和氧中选择的一个、两个或三个杂原子；R2选择氢、甲基和乙基；I）R3为氢、甲基或乙基；R4和R5独立选择自乙基和异丙基；且R3、R4和R5共有至少6个碳原子；或II）R3、R4和R5中的任意两个或全部与它们所连接的碳原子形成3-对薄荷基、博尔尼基或金刚烷基；具有冷却性质，其用途为冷却剂和包括它们的组合物。

  公开号：

  US20120095042A1

文献信息

• Organic compounds having cooling properties
  申请人：Furrer Stefan Michael

  公开号：US08664261B2

  公开（公告）日：2014-03-04

  Provided are compounds of formula (I) wherein m is 0, 1 or 2; R1 is a mono- or bicyclic heterocyclic ring system including one, two or three heteroatoms selected from nitrogen, sulphur and oxygen; R2 is selected from hydrogen, methyl and ethyl; I) R3 is hydrogen, methyl, or ethyl; and R4 and R5 are independently selected from ethyl and isopropyl; and R3, R4 and R5 together have at least 6 carbon atoms; or II) any two or all of R3, R4 and R5 form together with the carbon atom to which they are attached 3-para-menthyl, bornyl, or adamantyl; having cooling properties, their use as cooling agent and compositions including them.

  提供的化合物式(I)如下： 其中， m为0、1或2； R1为单环或双环杂环环系，包括从氮、硫和氧中选择的一个、两个或三个杂原子； R2从氢、甲基和乙基中选择； (I) R3为氢、甲基或乙基；且 R4和R5独立地选择自乙基和异丙基； 同时，R3、R4和R5至少共有6个碳原子；或者 (II) R3、R4和R5中的任意两个或全部与它们附着的碳原子形成3-对薄荷基、伯基或金刚烷基； 这些化合物具有冷却特性，可用作冷却剂和包含它们的组合物。
• ORGANIC COMPOUNDS HAVING COOLING PROPERTIES
  申请人：Givaudan SA

  公开号：EP2427170A2

  公开（公告）日：2012-03-14
• US8664261B2
  申请人：——

  公开号：US8664261B2

  公开（公告）日：2014-03-04
• [EN] ORGANIC COMPOUNDS<br/>[FR] COMPOSÉS ORGANIQUES
  申请人：GIVAUDAN SA

  公开号：WO2010128026A2

  公开（公告）日：2010-11-11

  Provided are compounds of formula (I) wherein m is 0, 1 or 2; R1 is a mono- or bicyclic heterocyclic ring system comprising one, two or three heteroatoms selected from nitrogen, sulphur and oxygen; R2 is selected from hydrogen, methyl and ethyl; I) R3 is hydrogen, methyl, or ethyl; and R4 and R5 are independently selected from ethyl and isopropyl; and R3, R4 and R5 together comprise at least 6 carbon atoms; or II) any two or ail of R3, R4 and R5 form together with the carbon atom to which they are attached 3-para-menthyl, bornyl, or adamantly; having cooling properties, their use as cooling agent and compositions comprising them.
• Organic Compounds Having Cooling Properties
  申请人：Furrer Stefan Michael

  公开号：US20120095042A1

  公开（公告）日：2012-04-19

  Provided are compounds of formula (I) wherein m is 0, 1 or 2; R I is a mono- or bicyclic heterocyclic ring system including one, two or three heteroatoms selected from nitrogen, sulphur and oxygen; R 2 is selected from hydrogen, methyl and ethyl; I) R 3 is hydrogen, methyl, or ethyl; and R 4 and R 5 are independently selected from ethyl and isopropyl; and R 3 , R 4 and R 5 together have at least 6 carbon atoms: or II) any two or all of R 3 , R 4 and R 5 form together with the carbon atom to which they are attached 3-para-menthyl, bornyl, or adamantyl; having cooling properties, their use as cooling agent and compositions including them.

  提供的化合物为公式(I)，其中m为0、1或2；RI为单环或双环杂环环系统，包括从氮、硫和氧中选择的一个、两个或三个杂原子；R2选择氢、甲基和乙基；I）R3为氢、甲基或乙基；R4和R5独立选择自乙基和异丙基；且R3、R4和R5共有至少6个碳原子；或II）R3、R4和R5中的任意两个或全部与它们所连接的碳原子形成3-对薄荷基、博尔尼基或金刚烷基；具有冷却性质，其用途为冷却剂和包括它们的组合物。