(3R)-2-methyldec-1-en-3-ol | 1049684-87-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (3R)-2-methyldec-1-en-3-ol
• CAS: 1049684-87-8
• 化学式: C₁₁H₂₂O
• 分子量: 170.295
• InChiKey: BBCOPXHJKDGLRZ-LLVKDONJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-methyl-dec-1-en-3-one 在 硼烷-N,N-二乙基苯胺 、 chiral oxazaborolidine-based reagent 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 1.58h， 生成 (S)-2-methyl-3-octyl-propen-3-ol 、 (3R)-2-methyldec-1-en-3-ol
  参考文献：
  名称：

  Oxazaborolidine-Catalyzed Enantioselective Reduction of α-Methylene Ketones to Allylic Alcohols

  摘要：

  Oxazaborolidine-catalyzed enantioselective reduction of a-methylene ketones was efficiently carried out by using borane-diethylaniline as a stoichiometric reducing agent. The combination of this method and subsequent hydrogenation of thus-formed allylic alcohol improved stereoselectivity in the reduction of 24-oxocholesteryl ester to 24-(R)-hydroxycholesteryl ester.

  DOI：

  10.1021/jo8011013

文献信息

• NOVEL POLYMERS WHICH RESIST BACTERIAL ATTACHMENT
  申请人：Williams Paul

  公开号：US20140314826A1

  公开（公告）日：2014-10-23

  The invention provides a method for inhibiting bacterial attachment to a surface, the method comprising forming the surface from a polymer, or applying a polymer to the surface, wherein the polymer is a homopolymer formed from a (meth) acrylate or (meth) acrylamide monomer or a copolymer formed from one or more (meth) acrylate or (meth) acrylamide monomers, wherein the (meth) acrylate or (meth) acrylamide monomers are of formula (I) or (II): [H 2 C═CR′—C(═O)—O—] n R  (I) [H 2 C═CR′—C(═O)—NH—] n R  (II) wherein n is 1, 2 or 3, R′ is independently H or CH 3 , R is an organic group having a total of from 2 to 24 carbon atoms, wherein the organic group includes an aliphatic or aromatic hydrocarbon moiety and wherein the organic group does not include any hydroxyl groups.