allyl 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl-(1->2)-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1->3)-4,6-O-benzylidene-α-D-mannopyranoside | 638164-34-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: allyl 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl-(1->2)-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1->3)-4,6-O-benzylidene-α-D-mannopyranoside
• CAS: 638164-34-8
• 化学式: C₆₉H₆₂O₂₁
• 分子量: 1227.24
• InChiKey: JWWYJTAPHWZPEI-LHPLPFSISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.23
• 重原子数：
  90.0
• 可旋转键数：
  21.0
• 环数：
  11.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  251.87
• 氢给体数：
  1.0
• 氢受体数：
  21.0

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 allyl 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl-(1->2)-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1->3)-4,6-O-benzylidene-α-D-mannopyranoside 在 吡啶 作用下， 反应 12.0h， 以90.6%的产率得到allyl 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl-(1->2)-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1->3)-2-O-acetyl-4,6-O-benzylidene-α-D-mannopyranoside
  参考文献：
  名称：

  Facile syntheses of the hexasaccharide repeating unit of the exopolysaccharide from Cryptococcus neoformans serovar A

  摘要：

  Two hexasaccharides, beta-D-Xyip-(1 --> 2)-alpha-D-Manp-(1 --> 3)-[beta-D-Xylp-(1 --> 42)-]alpha-D-Manp-(1--> 3)-[beta-D-GlcpA-(1 --> 2)-]alpha-D-Manp and beta-D-GlcpA-(1 --> 2)-[beta-D-Manp-(1 --> 3)-[beta-D-XylP-(1 --> 2)-]alpha-D-Manp-(1 --> 3)-]alpha-D-Manp, the repeating unit of the exopolysaccharide from Cryptococcus neoformans serovar A, were synthesized as their methyl glycosides in a regio- and stereoselective manner. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/s0968-0896(03)00391-2
• 作为产物：
  描述：

  allyl 3,4,6-tri-O-benzoyl-α-D-mannopyranoside 在 三氟甲磺酸三甲基硅酯 、 sodium acetate 、 溶剂黄146 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 、 palladium dichloride 作用下， 以 二氯甲烷 为溶剂， 反应 18.0h， 生成 allyl 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl-(1->2)-3,4,6-tri-O-benzoyl-α-D-mannopyranosyl-(1->3)-4,6-O-benzylidene-α-D-mannopyranoside
  参考文献：
  名称：

  Facile syntheses of the hexasaccharide repeating unit of the exopolysaccharide from Cryptococcus neoformans serovar A

  摘要：

  Two hexasaccharides, beta-D-Xyip-(1 --> 2)-alpha-D-Manp-(1 --> 3)-[beta-D-Xylp-(1 --> 42)-]alpha-D-Manp-(1--> 3)-[beta-D-GlcpA-(1 --> 2)-]alpha-D-Manp and beta-D-GlcpA-(1 --> 2)-[beta-D-Manp-(1 --> 3)-[beta-D-XylP-(1 --> 2)-]alpha-D-Manp-(1 --> 3)-]alpha-D-Manp, the repeating unit of the exopolysaccharide from Cryptococcus neoformans serovar A, were synthesized as their methyl glycosides in a regio- and stereoselective manner. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/s0968-0896(03)00391-2