1,4-cyclohexanediyl diformate | 137174-95-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1,4-cyclohexanediyl diformate
• 英文别名: 4-formyloxycyclohexyl formate；(4-Formyloxycyclohexyl) formate
• CAS: 137174-95-9
• 化学式: C₈H₁₂O₄
• 分子量: 172.181
• InChiKey: YSWFGPABWNDMSZ-UHFFFAOYSA-N

物化性质

• 沸点：
  235.8±20.0 °C(Predicted)
• 密度：
  1.14±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  甲酸 、 1,4-环己二醇 在 对甲苯磺酰氯 作用下， 反应 0.63h， 以93%的产率得到1,4-cyclohexanediyl diformate
  参考文献：
  名称：

  对甲苯磺酰氯作为温和条件下羟基化合物乙酰化和甲酰化的新型有效催化剂

  摘要：

  据报道，在无溶剂条件下，对甲苯磺酰氯催化应用乙酸酐有效地乙酰化各种类型的醇和酚。同样基于在无溶剂条件下催化量的对甲苯磺酰氯的使用，使用甲酸使结构上不同的醇甲酰化。反应在较短的反应时间内进行，并且在室温下以良好至极好的收率进行。

  DOI：

  10.1016/j.cclet.2010.05.025

文献信息

• Highly selective monoacylation of symmetric diols catalyzed by metal sulfates supported on silica gel
  作者：Takeshi Nishiguchi、Katsumi Kawamine、Tomoko Ohtsuka

  DOI：10.1021/jo00027a054

  日期：1992.1

  Several 1,n-diols, ranging from 1,2-ethanediol to 1,16-hexadecanediol, were monoacylated with high selectivity by reaction with esters in the presence of metal sulfates or hydrogen sulfates, like Ce(SO4)2 and NaHSO4, supported on silica gel. Symmetrical secondary diols were also selectively monoformylated, by reaction with ethyl formate. This method of selective esterification is simple and practical. The yield of monoester depends upon both the composition and the volume of the solvent (an ester/alkane mixture). Unsupported NaHSO4 also catalyzed monoacylation, but the selectivity was less than in monoacylations catalyzed by the supported reagent. The selectivity can be explained by the following reasons: (1) monoacylated products are formed selectively because the diol, but not the monoester, is preferentially adsorbed on the surface of the catalysts, where esterification then occurs, and (2) thin diol layers are formed on the surface of the catalysts due to limited solubility of the diols in the solvent.
• Formylation of Alcohol with Formic Acid under Solvent-Free and Neutral Conditions Catalyzed by Free I2 or I2 Generated in situ from Fe(NO3)3·9H2O/NaI
  作者：Rostami AMIN、Khazaei ARDESHIR、Alavi-Nik HEIDAR ALI、Toodeh-Roosta ZAHRA

  DOI：10.1016/s1872-2067(10)60160-x

  日期：2011.1

  Different alcohols were formylated by formic acid under solvent-free conditions in the presence of iodine as the catalyst with good-to-high yields at room temperature. I-2 generated in situ from Fe(NO3)(3)center dot 9H(2)O/NaI also catalyzed the formylation of the alcohols under solvent-free conditions. This gives a green and efficient reaction at room temperature, in which the use of toxic and corrosive molecular I-2 is avoided.
• [EN] METHOD FOR PRODUCING COPOLYESTER, SURFACE MODIFICATION METHOD, AND BONDED OBJECT<br/>[FR] PROCÉDÉ DE PRODUCTION DE COPOLYESTER, PROCÉDÉ DE MODIFICATION DE SURFACE ET OBJET LIÉ<br/>[JA] ポリエステル共重合体の製造方法、表面改質方法、および接合体
  申请人：UNIV KYUSHU NAT UNIV CORP

  公开号：WO2021045088A1

  公开（公告）日：2021-03-11

  本発明の下記一般式（５）で表されるポリエステル共重合体の製造方法は、（Ａ）下記一般式（１）で表される化合物（ａ１）および下記一般式（２）で表される化合物（ａ２）、または下記一般式（３）で表されるポリマー（ａ３）と、（Ｂ）下記一般式（４）で表されるポリマーとを、エステル化触媒の存在下、有機溶媒中で反応させる工程を含む。