1,2-bis((4-ethyl-3,5-dimethyl-1H-pyrrol-2-yl)methylene)hydrazine | 1609521-91-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 1,2-bis((4-ethyl-3,5-dimethyl-1H-pyrrol-2-yl)methylene)hydrazine
• CAS: 1609521-91-6
• 化学式: C₁₈H₂₆N₄
• 分子量: 298.431
• InChiKey: DKOBTFXFUFHXGN-UHFFFAOYSA-N

物化性质

• 沸点：
  483.1±45.0 °C(predicted)
• 密度：
  1.06±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.15
• 重原子数：
  22.0
• 可旋转键数：
  5.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  56.3
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  三氟化硼乙醚 、 1,2-bis((4-ethyl-3,5-dimethyl-1H-pyrrol-2-yl)methylene)hydrazine 在 三乙胺 作用下， 以 甲苯 为溶剂， 反应 0.17h， 以43%的产率得到5,13-Diethyl-2,2,10,10-tetrafluoro-4,6,12,14-tetramethyl-3,11-diaza-1,9-diazonia-2,10-diboranuidatetracyclo[7.7.0.03,7.011,15]hexadeca-1(16),4,6,8,12,14-hexaene
  参考文献：
  名称：

  Highly Fluorescent BF₂ Complexes of Hydrazine–Schiff Base Linked Bispyrrole

  摘要：

  A series of BF2 complexes of hydrazine-Schiff base linked bispyrrole have been prepared from a simple two-step reaction from commercially available substances and are highly fluorescent in solution, film, and solid states with larger Stokes shift and excellent photostabilities comparable or even super to those of their BODIPY analogues. These resultant fluorescent dyes are highly susceptible to the postfunctionalization, as demonstrated in this work via the Knoevenagel condensation to introducing functionalities or tether groups to the chromophore.

  DOI：

  10.1021/ol501162f
• 作为产物：
  描述：

  4-乙基-3,5-二甲基-1H-吡咯-2-甲醛 在 溶剂黄146 、 肼 作用下， 以 乙醇 为溶剂， 以91%的产率得到1,2-bis((4-ethyl-3,5-dimethyl-1H-pyrrol-2-yl)methylene)hydrazine
  参考文献：
  名称：

  Highly Fluorescent BF₂ Complexes of Hydrazine–Schiff Base Linked Bispyrrole

  摘要：

  A series of BF2 complexes of hydrazine-Schiff base linked bispyrrole have been prepared from a simple two-step reaction from commercially available substances and are highly fluorescent in solution, film, and solid states with larger Stokes shift and excellent photostabilities comparable or even super to those of their BODIPY analogues. These resultant fluorescent dyes are highly susceptible to the postfunctionalization, as demonstrated in this work via the Knoevenagel condensation to introducing functionalities or tether groups to the chromophore.

  DOI：

  10.1021/ol501162f