2-(2,4-dihydroxyphenyl)benzotriazole-N-oxide | 108021-91-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-(2,4-dihydroxyphenyl)benzotriazole-N-oxide
• 英文别名: 4-(1-Oxidobenzotriazol-1-ium-2-yl)benzene-1,3-diol
• CAS: 108021-91-6
• 化学式: C₁₂H₉N₃O₃
• 分子量: 243.222
• InChiKey: PIXQULGYRYOKOJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  83.7
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Sunscreen Cosmetics
  申请人：Araki Hidefumi

  公开号：US20100221199A1

  公开（公告）日：2010-09-02

  The present invention is a sunscreen cosmetic comprising 4-(1,1-dimethylethyl)-4′-methoxydibenzoylmethane, a benzotriazole derivative represented by the following general formula (I), and ethylhexyl 2-cyano-3,3-diphenylacrylate. The present invention is a sunscreen cosmetic comprising hexyl diethylaminohydroxybenzoylbenzoate and a benzotriazole derivative represented by the following general formula (I). (In this formula, R′=a straight chain alkyl group of C1-C6 and R″=a straight chain alkyl group of C1-C3.) The object of the present invention is to provide a sunscreen cosmetic that prevents staining due to secondary adhesion to clothing.

  本发明是一种防晒化妆品，包括4-(1,1-二甲基乙基)-4'-甲氧基二苯甲酰甲烷、以下通式(I)所表示的苯并三唑衍生物和乙基己基2-氰基-3,3-二苯基丙烯酸酯。本发明是一种防晒化妆品，包括己基二乙氨基羟基苯甲酰苯甲酸酯和以下通式(I)所表示的苯并三唑衍生物。（在此公式中，R′=碳数为1-6的直链烷基，R″=碳数为1-3的直链烷基。）本发明旨在提供一种防晒化妆品，可预防由于与衣物的次级附着而导致的染色。
• Sunscreen cosmetic composition
  申请人：Abe Koji

  公开号：US20090169494A1

  公开（公告）日：2009-07-02

  The present invention is a sunscreen cosmetic comprising 2,4-bis[[4-(2-ethylhexyloxy)-2-hydroxy]phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine and a specific benzotriazole derivative. Also, the present invention is a sunscreen cosmetic comprising a specific benzotriazole derivative and a specific alkylaryl 1,3-propanedione silicone derivative. An object of the present invention is to provide a sunscreen cosmetic that exhibits superior UV-A absorption capacity and excellent stability and also sufficiently dissolves 2,4-bis[[4-(2-ethylhexyloxy)-2-hydroxy]phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine, which has low solubility and crystallizes easily. Another object is to provide a sunscreen cosmetic that can synergistically improve the ultraviolet absorption capacity of conventional ultraviolet absorbents.

  本发明是一种防晒化妆品，包括2,4-双[[4-(2-乙基己氧基)-2-羟基]苯基]-6-(4-甲氧基苯基)-1,3,5-三嗪和特定的苯并三唑衍生物。此外，本发明还是一种防晒化妆品，包括特定的苯并三唑衍生物和特定的烷基芳基1,3-丙二酮硅氧烷衍生物。本发明的目的是提供一种具有优异的UV-A吸收能力和优异稳定性的防晒化妆品，同时也能充分溶解2,4-双[[4-(2-乙基己氧基)-2-羟基]苯基]-6-(4-甲氧基苯基)-1,3,5-三嗪，该化合物溶解度低且易结晶。另一个目的是提供一种能够协同改善传统紫外线吸收剂的紫外线吸收能力的防晒化妆品。
• Method of preparing 2-phenylbenzotriazoles
  申请人：CHEMIPRO KASEI KAISHA, LTD.

  公开号：EP0380840A1

  公开（公告）日：1990-08-08

  A method of preparing a 2-phenylbenzotriazole of formula I wherein R₁ is H, Cl, C₁₋₄ alkyl, C₁₋₄ alkoxy, COOH or SO₃H; R₂ is H, Cl, C₁₋₄ alkyl or C₁₋₄ alkoxy; R₃ is H, Cl, C₁₋₁₂ alkyl, C₁₋₄ alkoxy, phenyl, (C₁₋₈ alkyl)phenyl, phenoxy or phenyl(C₁₋₄ alkyl); R₄ is H, Cl, OH or C₁₋₄ alkoxy; and R₅ is H, C₁₋₁₂ alkyl or phenyl(C₁₋₄ alkyl); which comprises reducing with hydrogen the corresponding 2-phenylbenzotriazole-N-oxide of formula II

  一种制备式 I 的 2-苯基苯并三唑的方法 其中 R₁ 是 H、Cl、C₁₋₄ 烷基、C₁₋₄ 烷氧基、COOH 或 SO₃H；R₂ 是 H、Cl、C₁₋₄ 烷基或 C₁₋₄ 烷氧基；R₃ 是 H、Cl、C₁₋₁₂烷基、C₁₋₄ 烷氧基、苯基、(C₁₋₈烷基)苯基、苯氧基或苯基(C₁₋₄ 烷基)；R₄ 是 H、Cl、OH 或 C₁₋₄ 烷氧基；以及 R₅ 是 H、C₁₋₁₂烷基或苯基（C₁₋₄ 烷基）；其中包括用氢还原相应的式 II 的 2-苯基苯并三唑-N-氧化物
• Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides
  申请人：CHEMIPRO KASEI KAISHA, LTD.

  公开号：EP0257151B1

  公开（公告）日：1992-01-29
• US4780541A
  申请人：——

  公开号：US4780541A

  公开（公告）日：1988-10-25