| 1245746-18-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• CAS: 1245746-18-2
• 化学式: C₁₉H₁₉N₃O
• 分子量: 305.379
• InChiKey: LWSASSIUNYSQME-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  N-(2-methylbenzylidine)phenylglycine amide 、 、 、 、 生成 (2S)-N-(2-methylbenzylidine)phenylglycine amide 、 (2S)-N-(2-methylbenzylidine)phenylglycine amide 、 racemic N-(2-methylbenzylidene)-alanylamide 、 (2S)-3-methyl-2-[(2-methylphenyl)methylideneamino]butanamide 、 (2R)-3-methyl-2-[(2-methylphenyl)methylideneamino]butanamide 、 (2R)-2-[(2-methylphenyl)methylideneamino]-4-methylsulfanylbutanamide 、 (2S)-2-[(2-methylphenyl)methylideneamino]-4-methylsulfanylbutanamide 、 (2R)-3-(1H-indol-3-yl)-2-[(2-methylphenyl)methylideneamino]propanamide 、 (2S)-3-(1H-indol-3-yl)-2-[(2-methylphenyl)methylideneamino]propanamide
  参考文献：
  名称：

  Attrition-enhanced total resolution leads to homochiral families of amino acid derivatives

  摘要：

  The total resolution of five structurally similar racemizable amino acid derivatives, three of which have racemic crystal structures, was performed simultaneously. By enantioselective incorporation in an amino acid derivative that forms a conglomerate the other four were deracemized on attrition-induced grinding. The outcome of the resolution was random (R) or (S), but all compounds had the same absolute configuration and high enantiomeric purities. (C) 2010 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetasy.2010.04.007