| 1245746-16-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1245746-16-0
• 化学式: C₁₁H₁₄N₂O
• 分子量: 190.245
• InChiKey: ZZSAAWIXLQBMMM-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 (2S)-N-(2-methylbenzylidine)phenylglycine amide 作用下， 以 乙腈 为溶剂， 反应 336.0h， 生成 (2R)-2-[(2-methylphenyl)methylideneamino]propanamide 、 racemic N-(2-methylbenzylidene)-alanylamide
  参考文献：
  名称：

  Noorduin, Wim L.; Asdonk, Pim van der; Meekes, Hugo, Angewandte Chemie, International Edition, 2009, vol. 48, p. 3278 - 3280

  摘要：

  DOI：

文献信息

• Attrition-enhanced total resolution leads to homochiral families of amino acid derivatives
  作者：Michel Leeman、Jesse M. de Gooier、Karin Boer、Karen Zwaagstra、Bernard Kaptein、Richard M. Kellogg

  DOI：10.1016/j.tetasy.2010.04.007

  日期：2010.5

  The total resolution of five structurally similar racemizable amino acid derivatives, three of which have racemic crystal structures, was performed simultaneously. By enantioselective incorporation in an amino acid derivative that forms a conglomerate the other four were deracemized on attrition-induced grinding. The outcome of the resolution was random (R) or (S), but all compounds had the same absolute configuration and high enantiomeric purities. (C) 2010 Published by Elsevier Ltd.