2-oxo-3-(2-(prop-2-ynyloxy)phenoxy)propyl acetate | 1191256-33-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-oxo-3-(2-(prop-2-ynyloxy)phenoxy)propyl acetate
• 英文别名: [2-Oxo-3-(2-prop-2-ynoxyphenoxy)propyl] acetate
• CAS: 1191256-33-3
• 化学式: C₁₄H₁₄O₅
• 分子量: 262.262
• InChiKey: ITJOANPDLZVOJX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  61.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  1,2-bis(prop-2-ynyloxy)benzene 、 碘苯二乙酸 在 溶剂黄146 作用下， 反应 24.0h， 以51%的产率得到2-oxo-3-(2-(prop-2-ynyloxy)phenoxy)propyl acetate
  参考文献：
  名称：

  The reaction of terminal alkynes with PhI(OAc)2: a convenient procedure for the preparation of α-acyloxy ketones

  摘要：

  Treatment of terminal alkynes with PhI(OAc)(2) in different acids at 70 degrees C provided the corresponding alpha-acyloxy ketones in good to excellent yields. A plausible mechanism has been proposed based on the experimental results. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.07.081

文献信息

• The reaction of terminal alkynes with PhI(OAc)2: a convenient procedure for the preparation of α-acyloxy ketones
  作者：Dong-Liang Mo、Li-Xin Dai、Xue-Long Hou

  DOI：10.1016/j.tetlet.2009.07.081

  日期：2009.10

  Treatment of terminal alkynes with PhI(OAc)(2) in different acids at 70 degrees C provided the corresponding alpha-acyloxy ketones in good to excellent yields. A plausible mechanism has been proposed based on the experimental results. (C) 2009 Elsevier Ltd. All rights reserved.