ethyl 4,6-dioxoheptanoate | 20754-03-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 英文名称: ethyl 4,6-dioxoheptanoate
• 英文别名: 4,6-dioxo-heptanoic acid ethyl ester；4,6-Dioxo-heptansaeure-aethylester；4.6-Dioxo-heptansaeure-ethylester；1-Aethoxy-heptantrion-(1,4,6)
• CAS: 20754-03-4
• 化学式: C₉H₁₄O₄
• 分子量: 186.208
• InChiKey: CWICPWJRZJARAL-UHFFFAOYSA-N

物化性质

• 沸点：
  140-141 °C(Press: 13 Torr)
• 密度：
  1.065±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  60.4
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  ethyl 4,6-dioxoheptanoate 在 potassium carbonate 、 溶剂黄146 作用下， 以 丙酮 为溶剂， 反应 1.0h， 生成 ethyl 3-<2-(ethoxycarbonyl)ethyl>-4-<2-(methoxycarbonyl)ethyl>-5-methylpyrrole-2-carboxylate
  参考文献：
  名称：

  Pyrrole chemistry. An improved synthesis of ethyl pyrrole-2-carboxylate esters from diethyl aminomalonate

  摘要：

  DOI：

  10.1021/jo00350a033
• 作为产物：
  描述：

  2-Acetyl-3-oxo-adipinsaeure-diaethylester 在 水 作用下， 生成 ethyl 4,6-dioxoheptanoate
  参考文献：
  名称：

  Gelin,R.; Gelin,S., Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1964, vol. 258, p. 4783 - 4784

  摘要：

  DOI：

文献信息

• Intramolecular hydrogen bonding and linear pentapyrrole conformation
  作者：D. Timothy Anstine、David A. Lightner

  DOI：10.1007/s00706-014-1198-5

  日期：2014.7

  0H)-dipyrrinone. 13C NMR and 1H NMR measurements in (CD3)2SO confirmed the pentapyrrole structures, while 1H NMR data indicate intramolecular hydrogen bonding between the CO2H and dipyrrinone groups. Molecular mechanics modeling studies suggest stable U-shape conformations capable of encapsulating small planar aromatic molecules.

  三种新的线性五吡咯红宝石类似物：2,3,7,8,17,18,22,23-octamethyl-12,13-bis-(2-carboxyethyl)-1,10,15,24,25,27,28 ,29-八氢-27H-pentapyrrin-1,24-dione 和 2,3,8,12,13,17,22,23-octamethyl-7,18-bis-(2-carboxyethyl)-1,10,15 ,24,25,26,27,28, 29-octahydro-27H-pentapyrrin-1,24-dione 及其 7,18-二己酸类似物分别由 2,3,7,8-四甲基- (10H)-dipyrrin-2-one，来自 2,3,8-trimethyl-7-[2-(甲氧基羰基)乙基]-(10H)-dipyrrinone，和 2,3,8-trimethyl-7-[5- (甲氧基羰基)戊基]-(10H)-二吡啉酮。(CD3)2SO
• [EN] AZABICYCLO QUINOLONE CARBOXYLIC ACIDS
  申请人：PFIZER INC.

  公开号：WO1991002526A1

  公开（公告）日：1991-03-07

  (EN) Quinolone carboxylic acids 7-substituted by azabicyclo groups have antibacterial activity.(FR) Des acides quinolones carboxyliques substitués en 7 par des groupes azabicyclo ont une activité antibactérienne.

  (EN) Quinolone carboxylic acids 7-substituted by azabicyclo groups have antibacterial activity. 翻译成中文：由azabicyclo基团7-取代的喹诺酮羧酸具有抗菌活性。 (FR) Des acides quinolones carboxyliques substitués en 7 par des groupes azabicyclo ont une activité antibactérienne. 翻译成中文：由azabicyclo基团在7位取代的喹诺酮羧酸具有抗菌活性。
• Ice adhesion reducing prepolymers and polymers
  申请人：The Boeing Company

  公开号：US10202523B2

  公开（公告）日：2019-02-12

  The present disclosure relates to an FPOSS prepolymer which may be reacted with a reactive coating or a polyisocyanate and/or one or more of a polysiloxane, a polyol, a polyamine and a reactive coating; an FPOSS polyisocyanate prepolymer which may be reacted with one or more of a polysiloxane, a polyol, a polyamine or a reactive coating; and an FPOSS siloxane prepolymer which may be reacted with a polyisocyanate and/or one or more of a polyol, a polyamine or a reactive coating to form cross-linked polymers capable of reducing the ability of ice to adhere to the surface of an object, in particular aircraft or other vehicles, methods of producing the prepolymers and polymers and their use in coating surfaces.

  本公开涉及一种FPOSS预聚物，它可与活性涂层或多异氰酸酯和/或聚硅氧烷、多元醇、多胺和活性涂层中的一种或多种反应；一种FPOSS多异氰酸酯预聚物，它可与聚硅氧烷、多元醇、多胺或活性涂层中的一种或多种反应；一种 FPOSS 硅氧烷预聚物，可与多异氰酸酯和/或多元醇、多胺或活性涂层中的 一种或多种反应，以形成交联聚合物，从而降低冰附着在物体（尤其是飞机或其 他车辆）表面的能力；以及预聚物和聚合物的生产方法及其在表面涂层中的用途。
• Gelin,S.; Rouet,J., Bulletin de la Societe Chimique de France, 1971, p. 2179 - 2184
  作者：Gelin,S.、Rouet,J.

  DOI：——

  日期：——
• What Happens to the State in Conflict?: Political Analysis as a Tool for Planning Humanitarian Assistance
  作者：Lionel Cliffe、Robin Luckham

  DOI：10.1111/1467-7717.00150

  日期：2000.12

  It is now part of received wisdom that humanitarian assistance in conflict and post‐conflict situations may be ineffective or even counterproductive in the absence of an informed understanding of the broader political context in which so‐called ‘complex political emergencies’ (CPEs) occur. Though recognising that specific cases have to be understood in their own terms, this article offers a framework for incorporating political analysis in policy design. It is based on a programme of research on a number of countries in Africa and Asia over the last four years. It argues that the starting‐point should be an analysis of crises of authority within contemporary nation‐states which convert conflict (a feature of all political systems) into violent conflict; of how such conflict may in turn generate more problems for, or even destroy, the state; of the deep‐rooted political, institutional and developmental legacies of political violence; and of the difficulties that complicate the restoration of legitimate and effective systems of governance after the ‘termination’ of conflict. It then lists a series of questions which such an analysis would need to ask — less in order to provide a comprehensive check‐list than to uncover underlying political processes and links. It is hoped these may be used not only to understand the political dynamics of emergencies, but also to identify what kinds of policy action should and should not be given priority by practitioners.