三[4-(3,3,4,4,5,5,5-七氟-2,2-二(三氟甲基)戊基)苯基]磷化氢 | 322647-82-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 三[4-(3,3,4,4,5,5,5-七氟-2,2-二(三氟甲基)戊基)苯基]磷化氢
• 中文别名: 四[4-(2,2-二(三氟甲基))-1H,1H,2H,2H-全氟苯基]苯基膦
• 英文名称: tris[4-(3,3,4,4,5,5,5-heptafluoro-2,2-bis(trifluoromethyl)pentyl)phenyl]phosphane
• 英文别名: Tris-[4-(3,3,4,4,5,5,5-heptafluoro-2,2-bis-trifluoromethylpentyl)phenyl]phosphane；Tris[4-(3,3,4,4,5,5,5-heptafluoro-2,2-bis(trifluoromethyl)pentyl)phenyl] phosphine；tris[4-[3,3,4,4,5,5,5-heptafluoro-2,2-bis(trifluoromethyl)pentyl]phenyl]phosphane
• CAS: 322647-82-5
• 化学式: C₃₉H₁₈F₃₉P
• 分子量: 1258.48
• InChiKey: ZHQHSVFPOKMCMF-UHFFFAOYSA-N

物化性质

• 沸点：
  519.3±50.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  19.8
• 重原子数：
  79
• 可旋转键数：
  15
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  39

安全信息

• WGK Germany：
  3

反应信息

• 作为产物：
  描述：

  1-溴-4-(碘甲基)苯 在 叔丁基锂 、 cesium fluoride 作用下， 以 乙醚 、 N,N-二甲基甲酰胺 、 正戊烷 为溶剂， 反应 50.0h， 生成 三[4-(3,3,4,4,5,5,5-七氟-2,2-二(三氟甲基)戊基)苯基]磷化氢
  参考文献：
  名称：

  Separation of “Light Fluorous” Reagents and Catalysts by Fluorous Solid-Phase Extraction:  Synthesis and Study of a Family of Triarylphosphines Bearing Linear and Branched Fluorous Tags

  摘要：

  Practical syntheses of new triarylphosphines bearing both linear and branched fluorous tags (Rf) are reported. The phosphines have one, two, or all three aryl rings bearing fluorous tags: (Ph)(3-n)P(C6H4(CH2)(m)Rf)(n) Fluorous-organic partition coefficients have been measured and the retention properties of both the phosphines and the derived phosphine oxides on fluorous reverse phase silica have been studied. While applications relying on liquid-liquid extractive separations of these phosphines may be limited to those bearing three fluorous chains, the technique of solid phase extraction should be broadly applicable to phosphines, phosphine oxides, and derived metal complexes. A parallel platinum-catalyzed allylation of aldehydes with fluorous allyl stannanes illustrates the usefulness of the new fluorous ligands in small-scale synthesis.

  DOI：

  10.1021/jo000464f

文献信息

• Fluorous phosphines and phosphine oxides
  申请人：——

  公开号：US20020183521A1

  公开（公告）日：2002-12-05

  A method of increasing the fluorous nature of a compound includes the step of reacting the compound with or tagging the compound with at least one of a second compound having the formula: 1 wherein R is an alkyl group or an aryl group, n is 1, 2 or 3 and Rs is a spacer group and Rf is a branched fluorous group. A chemical compound having the general formula: 2 wherein n, Rs and Rf are defined above.

  一种增加化合物氟亲和性的方法包括以下步骤：将化合物与具有以下公式的第二化合物反应或标记化合物：1其中R是烷基或芳基，n为1、2或3，Rs为间隔基团，Rf为分支氟亲和基团。化学化合物的通式为：2其中n、Rs和Rf如上定义。
• US6727390B2
  申请人：——

  公开号：US6727390B2

  公开（公告）日：2004-04-27
• [EN] FLUOROUS PHOSPHINES AND PHOSPHINE OXIDES<br/>[FR] PHOSPHINES FLUORITIQUES ET OXYDES DE PHOSPHINE
  申请人：UNIV PITTSBURGH

  公开号：WO2002081486A1

  公开（公告）日：2002-10-17

  A method of increasing the fluorous nature of a compound includes the step of reacting the compound with or tagging the compound with at least one of a second compound having the formula: wherein R is an alkyl group or an aryl group, n is 1, 2 or 3 and Rs is a spacer group and Rf is a branched fluorous group. A chemical compound having the general formula: wherein n, Rs and Rf are defined above.