4-乙氧基-3-甲氧基-苯甲醛肟 | 81259-53-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 4-乙氧基-3-甲氧基-苯甲醛肟
• 英文名称: 4-ethoxy-3-methoxy-benzaldehyde seqtrans-oxime
• 英文别名: 4-Aethoxy-3-methoxy-benzaldehyd-seqtrans-oxim；4-Ethoxy-3-methoxybenzaldehyde oxime；(NE)-N-[(4-ethoxy-3-methoxyphenyl)methylidene]hydroxylamine
• CAS: 81259-53-2
• 化学式: C₁₀H₁₃NO₃
• mdl: MFCD01070631
• 分子量: 195.218
• InChiKey: IMUTXONCNANTKW-YRNVUSSQSA-N

物化性质

• 熔点：
  100 °C
• 沸点：
  298.5±30.0 °C(Predicted)
• 密度：
  1.09±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  51
• 氢给体数：
  1
• 氢受体数：
  4

安全信息

• 海关编码：
  2928000090

反应信息

• 作为反应物：
  描述：

  4-乙氧基-3-甲氧基-苯甲醛肟 在 乙醚 、 水 作用下， 生成 4-ethoxy-3-methoxy-benzaldehyde seqcis-oxime
  参考文献：
  名称：

  Hann, Journal. Washington Academy of Sciences, Washington, D. C, 1934, vol. 24, p. 126

  摘要：

  DOI：
• 作为产物：
  描述：

  香草醛 在 氢氧化钾 作用下， 生成 4-乙氧基-3-甲氧基-苯甲醛肟
  参考文献：
  名称：

  Hann, Journal. Washington Academy of Sciences, Washington, D. C, 1934, vol. 24, p. 126

  摘要：

  DOI：

文献信息

• Chromosomal alterations and male infertility
  作者：A. Antonelli、L. Gandini、P. Petrinelli、L. Marcucci、R. Elli、F. Lombardo、F. Dondero、Andrea Lenzi

  DOI：10.1007/bf03343793

  日期：2000.11

  Reduced male fertility can be caused by genetic factors affecting gamete formation or function; in particular, chromosome abnormalities are a possible cause of male subfertility as shown by their higher frequency in infertile men than in the general male population. Meiotic studies in a number of these males have shown spermatogenesis breakdown, often related to alterations in the process of chromosome synapsis. Indeed, any condition that can interfere with X-Y bivalent formation and X-chromosome inactivation is critical to the meiotic process; furthermore, asynapsed regions may themselves represent a signal for the meiotic checkpoint that eliminates spermatocytes with synaptic errors. We performed cytogenetic, hormonal and seminal studies in 333 infertile patients selected because azoospermic, severely oligozoospermic or normozoospermic with failure to fertilize the partner's oocytes in an in vitro fertilization (IVF) program. Our findings: 1) confirm the high incidence of chromosomal anomalies among infertile males; 2) highlight the relevance in male infertility of quantitative/positional modifications of the constitutive heterochromatin; and 3) underline the relevance of cooperation between andrologists and cytogenetists prior to every kind of assisted reproduction, above all prior to intracytoplasmic sperm injection, in which selective hurdles eliminating abnormal germ cells are bypassed. (C) 2000, Editrice Kurtis.
• MIXED BENZOINS. VIII. FURTHER DETERMINATIONS OF STRUCTURES. QUESTION OF ISOMERS
  作者：Johannes S. Buck、Walter S. Ide

  DOI：10.1021/ja01347a043

  日期：1932.8
• Macchia; Orlandini; Rossello, Il Farmaco, 1994, vol. 49, # 12, p. 767 - 773
  作者：Macchia、Orlandini、Rossello、Bertini、Soldani、Baldacci、Gervasi

  DOI：——

  日期：——
• SCHLIEMANN, W., WISS. Z. M.-LUTHER-UNIV. HALLE-WITTENBERG. MATH.-NATURWISS. R., 1981, 30,+
  作者：SCHLIEMANN, W.

  DOI：——

  日期：——