(1,2-ethylenediamine)(malonato)palladium(II) | 52260-91-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (1,2-ethylenediamine)(malonato)palladium(II)
• CAS: 52260-91-0
• 化学式: C₅H₁₀N₂O₄Pd
• 分子量: 268.565
• InChiKey: SQSCJUFAYWUMMD-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  (1,2-ethylenediamine)(malonato)palladium(II) 以 neat (no solvent) 为溶剂， 生成 palladium(II) oxide
  参考文献：
  名称：

  Synthesis, characterization, solution equilibria and DNA binding of some mixed-ligand palladium(II) complexes. Thermodynamic models for carboplatin drug and analogous compounds

  摘要：

  A series of ternary complexes of palladium(II) with ethylenediamine (en) and dicarboxylate ligands of the type [Pd(en)L], where L = malonato (I), methylinalonato (II), dimethylmalonato (III) and 1,1-cyclobutanedicarboxylato (IV), were synthesized and characterized by elemental analysis, IR spectroscopy and TG-DTA thermal analysis. The X-ray crystal structures for the compounds H and IV are described. The stability of these dicarboxylato complexes in aqueous solution has been investigated by potentiometric measurements. The formation constants calculated for these dicarboxylato complexes and those reported in the literature for the corresponding hydroxo- and chloro- complexes of the Pd(en) moiety have been used to obtain species distribution diagrams. In addition, the interaction of the dicarboxylato complexes and the dichloro complex [Pd(en)Cl-2] (V) with DNA was studied by various methods. UV spectral data and melting curves do not reveal differences in the reactivity of these complexes with DNA. This and other features are correlated with the stability of the complexes studied. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0020-1693(02)01071-x
• 作为产物：
  描述：

  乙二胺氯化钯(II) 、 丙二酸 在 AgNO₃ 、 NaHCO₃ 作用下， 以 水 为溶剂， 以65%的产率得到(1,2-ethylenediamine)(malonato)palladium(II)
  参考文献：
  名称：

  Synthesis, characterization, solution equilibria and DNA binding of some mixed-ligand palladium(II) complexes. Thermodynamic models for carboplatin drug and analogous compounds

  摘要：

  A series of ternary complexes of palladium(II) with ethylenediamine (en) and dicarboxylate ligands of the type [Pd(en)L], where L = malonato (I), methylinalonato (II), dimethylmalonato (III) and 1,1-cyclobutanedicarboxylato (IV), were synthesized and characterized by elemental analysis, IR spectroscopy and TG-DTA thermal analysis. The X-ray crystal structures for the compounds H and IV are described. The stability of these dicarboxylato complexes in aqueous solution has been investigated by potentiometric measurements. The formation constants calculated for these dicarboxylato complexes and those reported in the literature for the corresponding hydroxo- and chloro- complexes of the Pd(en) moiety have been used to obtain species distribution diagrams. In addition, the interaction of the dicarboxylato complexes and the dichloro complex [Pd(en)Cl-2] (V) with DNA was studied by various methods. UV spectral data and melting curves do not reveal differences in the reactivity of these complexes with DNA. This and other features are correlated with the stability of the complexes studied. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0020-1693(02)01071-x

文献信息

• Magnetic Circular Dichroism and Electronic Absorption Spectra of Mixed (Amine)(carboxylato) Complexes with the [Pd(N)<i>_n</i>(O)_4–<i>n</i>]-type (<i>n</i>=0–4)
  作者：Kazuhiko Nakayama、Takashi Komorita、Yoichi Shimura

  DOI：10.1246/bcsj.57.2930

  日期：1984.10

  Mixed-ligand [Pd(N)n(O)4–n]-type complexes constituting a long systematic series (n=0–4) were synthesized. Ammonia, ethylenediamine, rac-propylenediamine, trimethylenediamine, glycinate, β-alaninate, acetate, oxalate, and malonate were employed as ligands. Their magnetic circular dichroism (MCD) and electronic absorption spectra were discussed together with the CD spectra of the corresponding optically active complexes. The results strongly suggest that the dispersion of MCD observed in the spin-allowed d-d region is primarily a composite of B terms. Moreover, the MCD in the charge transfer region was found to be qualitatively additive with respect to contributions by the constituent ligands. From a detailed examination of the spin-allowed d-d absorption bands, it is noted that the substitution of an N,O-ligand for an N,N-ligand largely affects neither the band area nor band width whereas that of an O,O-ligand for an N,O-ligand does.

  合成了一系列长链的混合配体[Pd(N)n(O)4–n]-型配合物（n=0-4）。 氨、乙二胺、外消旋丙二胺、三甲基二胺、甘氨酸、β-丙氨酸、乙酸盐、草酸盐和丙二酸盐被用作配体。 讨论了它们的磁圆二色性（MCD）和电子吸收光谱以及相应光学活性配合物的CD光谱。 结果有力地表明，在自旋允许的d-d区域观察到的MCD的分散主要是B项的复合。 此外，在电荷转移区域，MCD被定性为与组成配体的贡献相加。 从对自旋允许的d-d吸收带的详细检查中可以看出，用N,O-配体代替N,N-配体对带面积和带宽度的影响不大，而用O,O-配体代替N,O-配体则会产生影响。