5-{2,4-dihydroxy-5-[N-(pyrazin-2-ylmethyl)-N-methylaminosulfonyl]phenyl}-4-(2-chlorophenyl)-3-hydroxy-4H-1,2,4-triazole | 958253-28-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 5-{2,4-dihydroxy-5-[N-(pyrazin-2-ylmethyl)-N-methylaminosulfonyl]phenyl}-4-(2-chlorophenyl)-3-hydroxy-4H-1,2,4-triazole
• 英文别名: 5-[4-(2-chlorophenyl)-5-oxo-1H-1,2,4-triazol-3-yl]-2,4-dihydroxy-N-methyl-N-(pyrazin-2-ylmethyl)benzenesulfonamide
• CAS: 958253-28-6
• 化学式: C₂₀H₁₇ClN₆O₅S
• 分子量: 488.911
• InChiKey: XVHFJWYIYFDFLR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  33
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  157
• 氢给体数：
  3
• 氢受体数：
  9

文献信息

• [EN] SUBSTITUTED PYRAZ INYLMETHYL SULFONAMIDES FOR USE AS. FUNGICIDES<br/>[FR] SULFONAMIDES DE PYRAZINYLMÉTHYLE SUBSTITUÉS CONVENANT COMME FONGICIDES
  申请人：BASF SE

  公开号：WO2009112523A1

  公开（公告）日：2009-09-17

  The present invention relates to the use of pyrazinylmethyl sulfonamides of formula (I) wherein Ra, n, R1, R2, R3, A, Y and D are as defined in the claims, and the N-oxides, and salts thereof for combating harmful fungi, and also to compositions and seed comprising at least one such compound. The invention also relates to novel substituted pyrazinylmethyl sulfonamides and processes and intermediates for preparing these compounds.

  本发明涉及使用式（I）的吡嗪甲基磺胺化合物，其中Ra、n、R1、R2、R3、A、Y和D如权利要求中所定义，以及其N-氧化物和盐，用于对抗有害真菌，以及包含至少一种这种化合物的组合物和种子。该发明还涉及新型取代的吡嗪甲基磺胺化合物，以及用于制备这些化合物的过程和中间体。
• TRIAZOLE DERIVATIVES II
  申请人：Eggenweiler Hans-Michael

  公开号：US20100022540A1

  公开（公告）日：2010-01-28

  Novel triazole derivatives of the formula (I) in which R 1 —R 6 and Y have the meanings indicated in Claim 1 , are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.

  新型三唑衍生物的化学式（I），其中R1—R6和Y具有索引在权利要求书中指示的含义，是HSP90抑制剂，可用于制备用于治疗HSP90在疾病中起作用的药物。
• TRIAZOLDERIVATE II
  申请人：Merck Patent GmbH

  公开号：EP2023922B1

  公开（公告）日：2012-07-11
• SUBSTITUTED PYRAZ INYLMETHYL SULFONAMIDES FOR USE AS. FUNGICIDES
  申请人：BASF SE

  公开号：EP2265592A1

  公开（公告）日：2010-12-29
• Substituted Pyrazinylmethyl Sulfonamides For Use As Fungicides
  申请人：Dietz Jochen

  公开号：US20110003691A1

  公开（公告）日：2011-01-06

  The present invention relates to the use of pyrazinylmethyl sulfonamides of formula (I) wherein R a , n, R 1 , R 2 , R 3 , A, Y and D are as defined in the claims, and the N-oxides, and salts thereof for combating harmful fungi, and also to compositions and seed comprising at least one such compound. The invention also relates to novel substituted pyrazinylmethyl sulfonamides and processes and intermediates for preparing these compounds.