N-(Ethylthiomethyl)morpholin | 51643-85-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: N-(Ethylthiomethyl)morpholin
• 英文别名: 4-ethylsulfanylmethyl-morpholine；4-(Aethylmercapto-methyl)-morpholin；4-(Ethylsulfanylmethyl)morpholine
• CAS: 51643-85-7
• 化学式: C₇H₁₅NOS
• 分子量: 161.268
• InChiKey: JORFFHZYFBRSDV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  37.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  双吗啉甲烷 、 乙硫醇 、 盐酸 以80%的产率得到
  参考文献：
  名称：

  LE FLOSH Y., BULL. SOC. CHIM. FRANCE, 1978, PART 2, NO 11-12, 595-601

  摘要：

  DOI：

文献信息

• Auto-ignition method
  申请人：CALIFORNIA RESEARCH CORP

  公开号：US02823515A1

  公开（公告）日：1958-02-18
• OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF
  申请人：WAVE LIFE SCIENCES LTD.

  公开号：US20190127733A1

  公开（公告）日：2019-05-02

  Among other things, the present disclosure relates to designed oligonucleotides, compositions, and methods thereof. In some embodiments, provided oligonucleotide compositions provide altered splicing of a transcript. In some embodiments, provided oligonucleotide compositions have low toxicity. In some embodiments, provided oligonucleotide compositions provide improved protein binding profiles. In some embodiments, provided oligonucleotide compositions have improved delivery. In some embodiments, provided oligonucleotide compositions have improved uptake. In some embodiments, the present disclosure provides methods for treatment of diseases using provided oligonucleotide compositions.