3-(2-hydroxyimino-cyclohexyl)-1,3-diphenyl-propan-1-one oxime | 54608-04-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 3-(2-hydroxyimino-cyclohexyl)-1,3-diphenyl-propan-1-one oxime
• 英文别名: 3-(2-Hydroxyimino-cyclohexyl)-1,3-diphenyl-propan-1-on-oxim
• CAS: 54608-04-7
• 化学式: C₂₁H₂₄N₂O₂
• 分子量: 336.434
• InChiKey: UYGJADQTXBXXSS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.06
• 重原子数：
  25.0
• 可旋转键数：
  5.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  65.18
• 氢给体数：
  2.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  3-(2-hydroxyimino-cyclohexyl)-1,3-diphenyl-propan-1-one oxime 在 盐酸 、 苯 作用下， 生成 2,4-diphenyl-5,6,7,8-tetrahydroquinoline
  参考文献：
  名称：

  Cohesion in science lesson discourse: clarity, relevance and sufficient information

  摘要：

  This paper discusses linguistics in the teaching of science, specifically the key linguistic processes through which students learn, rather than the mechanics of classroom interaction. Integrated datasets from The Classroom Learning Project contain transcripts of videotaped lessons spliced with teacher and student interviews and annotated with a researcher's comments. To illustrate the role of language in determining the effectiveness of teaching and learning, an integrated data set for one Australian Year 9 (14 year old students) science lesson on 'Fibres and Fabrics' was analysed in terms of coherence and comprehension. The analysis demonstrates the importance of communication skills in the classroom and the value of language analysis in determining the effectiveness of teacher's instructions. This paper argues the need for teachers to consider the importance of learning as a linguistic milieu especially when teaching science in context. When teaching and learning in contextually, competent communication must include adequate, genuine, clear and relevant amounts of information.

  DOI：

  10.1080/09500690010025076
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 3-(2-hydroxyimino-cyclohexyl)-1,3-diphenyl-propan-1-one oxime
  参考文献：
  名称：

  Cohesion in science lesson discourse: clarity, relevance and sufficient information

  摘要：

  This paper discusses linguistics in the teaching of science, specifically the key linguistic processes through which students learn, rather than the mechanics of classroom interaction. Integrated datasets from The Classroom Learning Project contain transcripts of videotaped lessons spliced with teacher and student interviews and annotated with a researcher's comments. To illustrate the role of language in determining the effectiveness of teaching and learning, an integrated data set for one Australian Year 9 (14 year old students) science lesson on 'Fibres and Fabrics' was analysed in terms of coherence and comprehension. The analysis demonstrates the importance of communication skills in the classroom and the value of language analysis in determining the effectiveness of teacher's instructions. This paper argues the need for teachers to consider the importance of learning as a linguistic milieu especially when teaching science in context. When teaching and learning in contextually, competent communication must include adequate, genuine, clear and relevant amounts of information.

  DOI：

  10.1080/09500690010025076

文献信息

• Synthesis of novel N-hydroxy heterocycles via intramolecular reductive cyclization of diketoximes by NaBH3CN
  作者：Muthupandi Nagaraj、Muthusamy Boominathan、Shanmugam Muthusubramanian、Nattamai Bhuvanesh

  DOI：10.1039/c1ob05232b

  日期：——

  simple and efficient protocol for the construction of substituted piperazines, piperidines, thiomorpholines, decahydroquinolines, perhydrocyclopenta[b]pyridine, and pyrrolidines bearing N-hydroxy substituents through intramolecular reductive cyclization of diketoximes using sodium cyanoborohydride is described.

  描述了使用氰基硼氢化钠通过二酮肟的分子内还原环化反应来构建带有N-羟基取代基的取代哌嗪，哌啶，硫吗啉，十氢喹啉，全氢环戊[b]吡啶和吡咯烷的简单有效的方法。