(1-adamantyl)butyric acid | 15037-71-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (1-adamantyl)butyric acid
• 英文别名: 1-(1-Carboxy-propyl)-adamantan；2-(1-Adamantyl)butanoic acid
• CAS: 15037-71-5
• 化学式: C₁₄H₂₂O₂
• 分子量: 222.327
• InChiKey: MPHIRXYUPAJGEO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (1-Adamantyl)methyl p-toluenesulfonate 以 二甲基亚砜 为溶剂， 反应 60.0h， 生成 (1-adamantyl)butyric acid
  参考文献：
  名称：

  Lauria,F. et al., Farmaco, Edizione Scientifica, 1967, vol. 22, p. 681 - 691

  摘要：

  DOI：

文献信息

• Initiation and bonding of diamond and other thin films
  申请人：Bension, Rouvain M.

  公开号：EP0598361A1

  公开（公告）日：1994-05-25

  A method for initiating and bonding thin films on substrates is described. The method employs an interlayer comprising a self-assembling monolayer (SAM). The SAM is formed from monomers, one end of which are capable of bonding to the substrate, and the other end of which form a surface similar to, and capable of initiating the formation of a film. Additionally, compositions for monomers, methods for SAM formation, and methods for film formation are disclosed. In a preferred embodiment the thin film is comprised of diamond.

  本发明涉及一种在基板上启动和结合薄膜的方法。该方法采用包含自组装单层（SAM）的中间层。SAM由单体形成，其中一端能够与基板结合，另一端形成类似于表面，并能够启动膜的形成。此外，还公开了单体的组成，SAM形成的方法以及膜形成的方法。在优选实施例中，薄膜由金刚石组成。
• Method for Inhibition of Potential-Dependent Cation Channel
  申请人：Takatoku Hiroko

  公开号：US20130045177A1

  公开（公告）日：2013-02-21

  An excellent potential-dependent cation channel inhibitor or an excellent masking agent is provided. Disclosed is a method for inhibiting a potential-dependent cation channel or a method for masking olfaction, both of which include administering an adamantane derivate represented by the following formula (1) or a salt thereof [wherein R′ and R 2 are identical with or different from each other, and each represent a hydrogen atom or an alkyl group having 1 to 6 carbon atoms; and X represents —OH, —R 3 —OH (wherein R 3 represents an alkylene group having 1 to 6 carbon atoms), —NH 2 , —R 4 —NH 2 (wherein R 4 represents an alkylene group having 1 to 6 carbon atoms), —COOH, —R 5 —COOH (wherein R 5 represents an alkylene group having 1 to 6 carbon atoms), —CO-R 6 (wherein R 6 represents an alkyl group having 1 to 6 carbon atoms), —CO—R 7 —COO—R 8 (wherein R 7 represents an alkylene group having 1 to 6 carbon atoms, and R 8 represents an alkyl group having 1 to 6 carbon atoms), or —NHCO—R 9 (wherein R 9 represents an alkyl group having 1 to 6 carbon atoms)].
• US8481016B2
  申请人：——

  公开号：US8481016B2

  公开（公告）日：2013-07-09
• Lauria,F. et al., Farmaco, Edizione Scientifica, 1967, vol. 22, p. 681 - 691
  作者：Lauria,F. et al.

  DOI：——

  日期：——