4-(diallylammonio)butanoate | 746572-71-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-(diallylammonio)butanoate
• 英文别名: 4-[Bis(prop-2-enyl)azaniumyl]butanoate
• CAS: 746572-71-4
• 化学式: C₁₀H₁₇NO₂
• 分子量: 183.25
• InChiKey: YYWNJIGIQZJUOW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  44.6
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-(diallylammonio)butanoate 在 亚磷酸 、 甲烷磺酸 、 三氯化磷 作用下， 以82%的产率得到4-diallylamino-1-hydroxybutylidene-1,1-bisphosphonic acid
  参考文献：
  名称：

  Synthesis of a novel zwitterionic bisphosphonate cyclopolymer containing residues of alendronic acid

  摘要：

  The reaction of 4-(diallylammonio)butanoate, H3PO3 and PCl3 in CH3SO3H created water-insoluble 4-diallylamino-1-hydroxybutylidene-1,1-bisphosphonic acid!, a novel monomer that contained residues of the osteoporosis drug alendronic acid. Monomer (+/-) I, a zwitterionic tetraprotic acid, in the presence of 2 equivs. NaOH(aq) and the initiator ammonium persulfate, underwent cyclopolymerization to yield water-soluble poly(zwitterion-dianion) (+/- =) II. Under the influence of pH, H was equilibrated to water-soluble poly(zwitterion-trianion) (+/- equivalent to) III, polytetraanion (= =) IV, poly(zwitterion-anion) (+/- -) V, cationic polyelectrolyte (+) VI and water-insoluble polyzwitterion (+/-) VII. The solution properties of backbone charges were investigated, and protonation constants of several centers in IV were determined. Polymers that contained residues of alendronic acid should have applications in various fields, including the field of medicine. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.reactfunctpolym.2014.11.011
• 作为产物：
  描述：

  ethyl 4-(diallylamino)butanoate 在 lithium hydroxide monohydrate 、 sodium hydrogen sulfate 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 0.5h， 生成 4-(diallylammonio)butanoate
  参考文献：
  名称：

  N-烯丙基-α-氰基酯通过水解/乙烯形成/环化/克莱森重排序列的一锅转化为α-烯丙基-α-氰基内酰胺

  摘要：

  首次开发了分子内的烯酮氮杂-克莱森重排，以使得能够从N-烯丙基氨基酯立体选择性地合成α-烯丙基-α-氰基-内酰胺。当起始分子中存在不对称的双-N-烯丙基基团时，该反应还表现出优异的化学选择性。由1-脯氨酸短暂合成旋光性双环内酰胺证明了该方法的有效性。

  DOI：

  10.1021/acs.orglett.5b02843

文献信息

• JP2000159735A
  申请人：——

  公开号：JP2000159735A

  公开（公告）日：2000-06-13
• CROSS-LINKED DIALLYL QUATERNARY AMMONIUM SALT TETRAPOLYMERS AND METHODS THEREOF
  申请人：King Fahd University of Petroleum and Minerals

  公开号：US20160264690A1

  公开（公告）日：2016-09-15

  Cross-linked tetrapolymers made up of different diallyl zwitterionic diallyl quaternary ammonium salt monomers, with one of them functioning as a cross-linking monomer. The cross-linked terpolymers include a repeating unit with multiple ligand centers that different metal ions can bind to. The cross-linked tetrapolymers are cationic, zwitterionic and anionic, and can be in either an acidic form or a basic form. A method of removing metal ions from an aqueous solution with these cross-linked tetrapolymers is also described.
• QUATERNARY AMMONIUM SOLVATED TETRAPOLYMERS AND METHODS OF REMOVING CR(III) FROM SOLUTION USING THE TETRAPOLYMER
  申请人：KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

  公开号：US20180022840A1

  公开（公告）日：2018-01-25

  Cross-linked tetrapolymers made up of different diallyl zwitterionic diallyl quaternary ammonium salt monomers, with one of them functioning as a cross-linking monomer. The cross-linked terpolymers include a repeating unit with multiple ligand centers that different metal ions can bind to. The cross-linked tetrapolymers are cationic, zwitterionic and anionic, and can be in either an acidic form or a basic form. A method of removing metal ions from an aqueous solution with these cross-linked tetrapolymers is also described.
• US9790296B2
  申请人：——

  公开号：US9790296B2

  公开（公告）日：2017-10-17
• US9890228B1
  申请人：——

  公开号：US9890228B1

  公开（公告）日：2018-02-13