| 1025797-24-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• CAS: 1025797-24-3
• 化学式: C₁₉H₃₆O₄
• 分子量: 328.492
• InChiKey: GEQCFWMXOAPUGI-YELSFEHDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.14
• 重原子数：
  23.0
• 可旋转键数：
  15.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  66.76
• 氢给体数：
  2.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  在 吡啶 、 4-二甲氨基吡啶 、 AD-mix-α 、 甲基磺酰胺 作用下， 以 水 、 叔丁醇 为溶剂， 反应 27.0h， 生成
  参考文献：
  名称：

  槐糖脂衍生的多羟基脂肪酸

  摘要：

  AbstractStarting from 17‐hydroxyoleic acid, which is readily available from acid alcoholysis of sophorolipids, several new polyhydroxy fatty acids have been synthesized. These compounds contain from 2 to 4 hydroxy groups, in some instances combined with other functional groups. The added hydroxy groups can be incorporated in the C18 chain in a variety of geometries, for example spaced widely throughout the chain at C1, C8, and C17. This regiochemical control will be of use in structure/function studies involving materials constructed from these hydroxy fatty acids. A further benefit is that the hydroxy groups can be present in protected or free states. The principal reactions used to introduce extra hydroxy groups are selenium oxide‐mediated allylic hydroxylation, osmium‐catalyzed dihydroxylation, and borohydride reduction of a carboxylic ester. These new compounds are expected to be of use in a number of areas, but particularly as building blocks for polymers or components of lubricant formulations.

  DOI：

  10.1007/s11746-007-1054-4
• 作为产物：
  描述：

  (S,Z)-methyl 17-hydroxyoctadece-9-enoate 在 叔丁基过氧化氢 、 selenium(IV) oxide 、 溶剂黄146 作用下， 以 癸烷 、 二氯甲烷 为溶剂， 反应 48.0h， 以504 mg的产率得到
  参考文献：
  名称：

  槐糖脂衍生的多羟基脂肪酸

  摘要：

  AbstractStarting from 17‐hydroxyoleic acid, which is readily available from acid alcoholysis of sophorolipids, several new polyhydroxy fatty acids have been synthesized. These compounds contain from 2 to 4 hydroxy groups, in some instances combined with other functional groups. The added hydroxy groups can be incorporated in the C18 chain in a variety of geometries, for example spaced widely throughout the chain at C1, C8, and C17. This regiochemical control will be of use in structure/function studies involving materials constructed from these hydroxy fatty acids. A further benefit is that the hydroxy groups can be present in protected or free states. The principal reactions used to introduce extra hydroxy groups are selenium oxide‐mediated allylic hydroxylation, osmium‐catalyzed dihydroxylation, and borohydride reduction of a carboxylic ester. These new compounds are expected to be of use in a number of areas, but particularly as building blocks for polymers or components of lubricant formulations.

  DOI：

  10.1007/s11746-007-1054-4