methyl 5-(7-bromo-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate | 1373278-06-8
中文名称
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中文别名
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英文名称
methyl 5-(7-bromo-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate
英文别名
Methyl 5-[7-bromo-3-(4-fluorophenyl)-4-oxoquinazolin-2-yl]pentanoate
CAS
1373278-06-8
化学式
C20H18BrFN2O3
mdl
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分子量
433.277
InChiKey
CXBBJQHHSYXEGE-UHFFFAOYSA-N
BEILSTEIN
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EINECS
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
物化性质
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沸点：544.6±60.0 °C(Predicted)
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密度：1.44±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
计算性质
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辛醇/水分配系数(LogP)：3.7
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重原子数：27
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可旋转键数：7
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环数：3.0
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sp3杂化的碳原子比例：0.25
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拓扑面积：59
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氢给体数：0
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氢受体数：5
上下游信息
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下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— methyl 5-[7-cyano-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]pentanoate 1373278-62-6 C21H18FN3O3 379.391 —— methyl 5-(3-(4-fluorophenyl)-4-oxo-7-vinyl-3,4-dihydroquinazolin-2-yl)pentanoate 1373278-65-9 C22H21FN2O3 380.419 —— methyl 5-(7-ethynyl-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate 1373278-28-4 C22H19FN2O3 378.403 —— methyl 5-(3-(4-fluorophenyl)-7-formyl-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate 1373278-66-0 C21H19FN2O4 382.391 —— methyl 5-(3-(4-fluorophenyl)-7-((hydroxyimino)methyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate 1373278-67-1 C21H20FN3O4 397.406 —— methyl 5-[7-azido-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]pentanoate 1373278-72-8 C20H18FN5O3 395.393 —— methyl 5-(3-(4-fluorophenyl)-4-oxo-7-((trimethylsilyl)ethynyl)-3,4-dihydroquinazolin-2-yl)pentanoate 1373278-27-3 C25H27FN2O3Si 450.585 —— methyl 5-[3-(4-fluorophenyl)-7-(N-hydroxycarbamimidoyl)-4-oxo-3,4-dihydroquinazolin-2-yl]pentanoate 1373278-63-7 C21H21FN4O4 412.421 —— methyl 5-(3-(4-fluorophenyl)-4-oxo-7-(1H-pyrazol-3-yl)-3,4-dihydroquinazolin-2-yl)pentanoate 1373278-08-0 C23H21FN4O3 420.443 —— methyl 5-(3-(4-fluorophenyl)-4-oxo-7-(thiazole-5-yl)-3,4-dihydroquinazolin-2-yl)pentanoate 1373278-07-9 C23H20FN3O3S 437.495 —— 5-[3-(4-fluorophenyl)-4-oxo-7-(1H-1,2,3-triazol-4-yl)-3,4-dihydroquinazolin-2-yl]pentanoic acid 1373275-12-7 C21H18FN5O3 407.404 —— 5-(3-(4-fluorophenyl)-4-oxo-7-(1H-pyrazol-3-yl)-3,4-dihydroquinazolin-2-yl)pentanoic acid 1373274-54-4 C22H19FN4O3 406.416 —— 5-(3-(4-fluorophenyl)-4-oxo-7-(thiazole-5-yl)-3,4-dihydroquinazoline-2-yl)pentanoic acid 1373274-50-0 C22H18FN3O3S 423.468 —— methyl 5-(3-(4-fluorophenyl)-7-(1-methyl-1 H-1,2,3-triazol-4-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate 1373278-29-5 C23H22FN5O3 435.458 —— 5-(3-(4-fluorophenyl)-7-(1-methyl-1H-1,2,3-triazol-4-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid 1373274-81-7 C22H20FN5O3 421.431 —— methyl 5-[7-(4-cyclopropyl-1H-1,2,3-triazol-1-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]pentanoate 1373278-73-9 C25H24FN5O3 461.496 —— methyl 5-(3-(4-fluorophenyl)-4-oxo-7-(5-phenyl-4,5-dihydroisoxazol-3-yl)-3,4-dihydroquinazolin-2-yl)pentanoate 1373278-68-2 C29H26FN3O4 499.542 —— 5-{3-(4-fluorophenyl)-7-[1-(2-methylpropyl)-1H-1,2,3-triazol-4-yl]-4-oxo-3,4-dihydroquinazolin-2-yl}pentanoic acid 1373275-09-2 C25H26FN5O3 463.512 —— 5-(3-(4-fluorophenyl)-4-oxo-7-(5-phenyl-4,5-dihydroisoxazol-3-yl)-3,4-dihydroquinazolin-2-yl)pentanoic acid 1373274-86-2 C28H24FN3O4 485.515 —— methyl 5-[7-(1-benzyl-1H-1,2,3-triazol-4-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]pentanoate 1373278-69-3 C29H26FN5O3 511.556 —— methyl 5-{7-[1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl]-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl}pentanoate 1373278-70-6 C29H25F2N5O3 529.546 —— 5-[7-(1-benzyl-1H-1,2,3-triazol-4-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]pentanoic acid 1373275-10-5 C28H24FN5O3 497.529 —— methyl 5-(3-(4-fluorophenyl)-4-oxo-7-(5-(pyridin-4-yl)-1,2,4-oxadiazol-3-yl)-3,4-dihydroquinazolin-2-yl)pentanoate 1373278-64-8 C27H22FN5O4 499.501 —— 5-{7-[1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl]-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl}pentanoic acid 1373275-13-8 C28H23F2N5O3 515.519 —— (R)-5-(7-(5-benzyl-5-methyl-4,5-dihydroisoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid 1373277-55-4 C30H28FN3O4 513.568 —— 5-{3-(4-fluorophenyl)-4-oxo-7-[5-(pyridin-4-yl)-1,2,4-oxadiazol-3-yl]-3,4-dihydroquinazolin-2-yl}pentanoic acid 1373274-84-0 C26H20FN5O4 485.474 —— methyl 5-{3-(4-fluorophenyl)-4-oxo-7-[1-(pyridin-3-yl)-1H-1,2,3-triazol-4-yl]-3,4-dihydroquinazolin-2-yl}pentanoate 1373278-71-7 C27H23FN6O3 498.516 —— methyl 5-(7-(5-(4-fluorobenzyl)-1,2,4-oxadiazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate 1373278-96-6 C29H24F2N4O4 530.531 —— 5-{3-(4-fluorophenyl)-4-oxo-7-[1-(pyridin-3-yl)-1H-1,2,3-triazol-4-yl]-3,4-dihydroquinazolin-2-yl}pentanoic acid 1373275-17-2 C26H21FN6O3 484.49 —— 5-[3-(4-fluorophenyl)-7-(5-methyl-5-phenyl-4H-1,2-oxazol-3-yl)-4-oxoquinazolin-2-yl]pentanoic acid 1373279-12-9 C29H26FN3O4 499.542 —— 5-[3-(4-fluorophenyl)-7-[(5R)-5-methyl-5-phenyl-4H-1,2-oxazol-3-yl]-4-oxoquinazolin-2-yl]pentanoic acid 1373274-88-4 C29H26FN3O4 499.542 —— 5-[3-(4-fluorophenyl)-7-[(5S)-5-methyl-5-phenyl-4H-1,2-oxazol-3-yl]-4-oxoquinazolin-2-yl]pentanoic acid 1373274-87-3 C29H26FN3O4 499.542 —— 5-(7-(5-(4-fluorobenzyl)-1,2,4-oxadiazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoic acid 1373277-78-1 C28H22F2N4O4 516.504 —— 5-[3-(4-fluorophenyl)-7-[(5S)-5-(4-fluorophenyl)-5-methyl-4H-1,2-oxazol-3-yl]-4-oxoquinazolin-2-yl]pentanoic acid 1373275-60-5 C29H25F2N3O4 517.532 ——