4,4-Bis(4-phenylmethoxyphenyl)pentyl methanesulfonate | 184866-16-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,4-Bis(4-phenylmethoxyphenyl)pentyl methanesulfonate
• CAS: 184866-16-8
• 化学式: C₃₂H₃₄O₅S
• 分子量: 530.685
• InChiKey: DHTKADGYHNHUNJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  38
• 可旋转键数：
  13
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  70.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  4,4-Bis(4-phenylmethoxyphenyl)pentyl methanesulfonate 在 三乙胺 作用下， 以 二氯甲烷 、 二甲基亚砜 为溶剂， 反应 3.0h， 生成 S-[4-[4,4-bis(4-phenylmethoxyphenyl)pentyl-methylcarbamoyl]phenyl] N,N-dimethylcarbamothioate
  参考文献：
  名称：

  Synthesis of a Series of Focally-Substituted Organothiol Dendrons

  摘要：

  The synthesis of new organothiol-functionalized dendrons of generation 1-4 is described. Several modifications to the original method for preparation of dendrons are detailed that were found to improve the yield and aid in scale-up. A particularly advantageous method for preparation of an aromatic thiol is reported and is employed in this reaction sequence. Several uses of these dendrons are anticipated and briefly described.

  DOI：

  10.1021/jo961527q
• 作为产物：
  描述：

  双酚酸 在 4-二甲氨基吡啶 、 lithium aluminium tetrahydride 、 18-冠醚-6 、 potassium carbonate 、 三乙胺 作用下， 以 四氢呋喃 、 二氯甲烷 、 丙酮 为溶剂， 反应 88.0h， 生成 4,4-Bis(4-phenylmethoxyphenyl)pentyl methanesulfonate
  参考文献：
  名称：

  Synthesis of a Series of Focally-Substituted Organothiol Dendrons

  摘要：

  The synthesis of new organothiol-functionalized dendrons of generation 1-4 is described. Several modifications to the original method for preparation of dendrons are detailed that were found to improve the yield and aid in scale-up. A particularly advantageous method for preparation of an aromatic thiol is reported and is employed in this reaction sequence. Several uses of these dendrons are anticipated and briefly described.

  DOI：

  10.1021/jo961527q

文献信息

• Hybrid organic–inorganic, hexa-arm dendrimers based on an Mo6Cl8 core
  作者：Christopher B. Gorman、Wendy Y. Su、Hongwei Jiang、Christopher M. Watson、Paul Boyle

  DOI：10.1039/a901590f

  日期：——

  Dendrons with focal phenoxide groups were shown to substitute for triflate or methoxide ligands around an Mo6Cl8 core to form molecules of the form Mo6(µ3-Cl)8(OR)6 where R = dendrons with zero to two hyperbranches, respectively; these molecules represent a new type of metal cluster core dendrimer with six arms and high symmetry.

  研究表明，带有焦苯氧物基团的树枝状化合物可以替代围绕 Mo6Cl8 核心的三late 或甲氧基配体，形成 Mo6(µ3-Cl)8(OR)6 形式的分子，其中 R = 树枝状化合物，分别带有零到两个超分支；这些分子代表了一种具有六个臂和高度对称性的新型金属簇核心树枝状化合物。
• Synthetic Approaches to an Isostructural Series of Redox-Active, Metal Tris(bipyridine) Core Dendrimers
  作者：Young-Rae Hong、Christopher B. Gorman

  DOI：10.1021/jo0351116

  日期：2003.11.1

  Several types of six-armed, metal tris(bipyridine) core dendrimers were synthesized. Bis-4,4'-alkoxy bipyridine dendrons were prepared and employed to make tris(bipyridine) dendrimers. Although the ruthenium-centered and iron-centered dendrimers displayed quasi-reversible cyclic voltammetry, the analogous cobalt-centered complex did not. The synthesis of 4,4'-disubstituted bipyridines containing -CH2OR groups proceeded in low yield. The reactions of the dicarbanion of 4,4'-dimethyl bipyridine prepared with LDA and mesylate, triflate, and bromide groups were found to result in no or poor yields of carbon-carbon bond formation. Use of KDA in place of LDA resulted in much higher yields of dendritic bipyridines.
• Dendritic encapsulation-roles of cores and branches
  作者：Tyson L Chasse、Joshua C Yohannan、Namjin Kim、Qun Li、Zemin Li、Christopher B Gorman

  DOI：10.1016/s0040-4020(03)00435-6

  日期：2003.5

  Examples of new dendrimers are presented. In the first, the effect on electron transfer rate attenuation is investigated for two dendrimer isomers that differ only in the linkage (ortho- versus meta-l inked) of the phenyl ether units within one generation of the structure. Second, the effect of encapsulation on electrochemical and luminescence behavior of a new type of rhenium selenide cluster core dendrimer is illustrated. (C) 2003 Elsevier Science Ltd. All rights reserved.
• Synthesis of a Series of Focally-Substituted Organothiol Dendrons
  作者：Kang-Yi Chen、Christopher B. Gorman

  DOI：10.1021/jo961527q

  日期：1996.1.1

  The synthesis of new organothiol-functionalized dendrons of generation 1-4 is described. Several modifications to the original method for preparation of dendrons are detailed that were found to improve the yield and aid in scale-up. A particularly advantageous method for preparation of an aromatic thiol is reported and is employed in this reaction sequence. Several uses of these dendrons are anticipated and briefly described.