1-[(6-methacryloyloxy)hexyl]-3-methylimidazolium bromide | 1015722-61-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-[(6-methacryloyloxy)hexyl]-3-methylimidazolium bromide
• 英文别名: 1-[6-(Methacryloyloxy)hexyl]-3-methylimidazolium bromide；6-(3-methylimidazol-3-ium-1-yl)hexyl 2-methylprop-2-enoate;bromide
• CAS: 1015722-61-8
• 化学式: Br*C₁₄H₂₃N₂O₂
• 分子量: 331.253
• InChiKey: MIAHRDWDHPBTLI-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.0
• 重原子数：
  19.0
• 可旋转键数：
  8.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  35.11
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  6-溴正己醇 在 2,6-二叔丁基-4-甲基苯酚 作用下， 以 乙腈 为溶剂， 反应 96.0h， 生成 1-[(6-methacryloyloxy)hexyl]-3-methylimidazolium bromide
  参考文献：
  名称：

  New Method for Synthesis of Methacrylate-Type Polymerizable Ionic Liquids

  摘要：

  A new method for the synthesis of polymerizable ionic liquids bearing a methacrylate moiety was developed with the aim to avoid premature polymerization of synthesized compounds. Spacer length between the imidazolium cation and the polymerizable functional group varied from 2 to 10 carbon atoms. Different 1-(n-hydroxyalkyl)-3-methylimidazolium bromides and 1-[n-(methacryloyloxy)-alkyl]-3-methylimidazolium bromides were obtained with very good yields (more than 90%). [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) for the following free supplemental resource: Full experimental and spectral details.]

  DOI：

  10.1080/00397911.2012.745159

文献信息

• Antibacterial surfaces based on poly(cationic liquid) brushes: switchability between killing and releasing via anion counterion switching
  作者：Yi-Shi Dong、Xin-Hong Xiong、Xiao-Wen Lu、Zhao-Qiang Wu、Hong Chen

  DOI：10.1039/c6tb01464j

  日期：——

  The surface consists of counterion-responsive poly(cationic liquid) brushes of poly(1-(2-methacryloyloxyhexyl)-3-methylimidazolium bromide) (PIL(Br)), the properties of which can be switched repeatedly between bacterial killing and bacterial release. Upon counter-anion exchange of PIL(Br) chains using lithium bis(trifluoromethanesulfonyl) amide (LiTf2N) to yield PIL(Tf2N), the wettability of the surface

  据报道，智能抗菌表面的发展既可以杀死附着的活细菌，又可以释放死细菌。该表面由对（1-（2-甲基丙烯酰氧基己基）-3-甲基咪唑鎓溴化物）（PIL（Br））的抗离子反应性的聚阳离子刷组成，可以在杀细菌和释放细菌之间反复切换其特性。 。使用双（三氟甲磺酰基）氨基锂（LiTf2N）进行PIL（Br）链的阴离子交换后，生成PIL（Tf2N），表面的润湿性从亲水性（水接触角〜52°）变为疏水性（〜97°）。 ）。PIL（Br）链采用具有杀菌特性的扩展构象。将阴离子转换为PIL（Tf2N）会产生折叠的链构象，从而释放出被杀死的细菌。表面的可切换杀伤和释放作用在三个周期内得以维持。因此可以得出结论，PIL（Br）层为“智能”抗菌表面的制造提供了可行的方法。