N-[3-Methoxy-4-(5-oxazolyl)phenyl]-N-methyl-5-phenyl-2-oxazolamine | 267645-91-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-[3-Methoxy-4-(5-oxazolyl)phenyl]-N-methyl-5-phenyl-2-oxazolamine
• 英文别名: N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-N-methyl-5-phenyl-1,3-oxazol-2-amine
• CAS: 267645-91-0
• 化学式: C₂₀H₁₇N₃O₃
• 分子量: 347.373
• InChiKey: KPVKSGIQAQWQNK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  64.5
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Metabolism-modulating agents and uses therefor
  申请人：Whitehead Paul Jonathan

  公开号：US20060106097A1

  公开（公告）日：2006-05-18

  The present invention is directed to methods and agents for modulating adipogenesis. More particularly, the present invention relates to molecules that modulate the level or functional activity of inosine-5′ monophosphate dehydrogenase (IMPDH) and to their use in modulating the accumulation of lipids in adipocytes and/or the differentiation of preadipocytes to adipocytes for treating or preventing adiposity-related conditions including, but not limited to, obesity, lipoma, lipomatosis, cachexia or lipodystrophy or the loss of adipose tissue in trauma or atrophic conditions.
• US6399773B1
  申请人：——

  公开号：US6399773B1

  公开（公告）日：2002-06-04
• US7915255B2
  申请人：——

  公开号：US7915255B2

  公开（公告）日：2011-03-29