p-Toluolsulfonsaeure-(4-acetoxy-butylester) | 19859-06-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: p-Toluolsulfonsaeure-(4-acetoxy-butylester)
• 英文别名: Butan-1,4-diolacetat-tosylat；4-(4-Methylphenyl)sulfonyloxybutyl acetate
• CAS: 19859-06-4
• 化学式: C₁₃H₁₈O₅S
• 分子量: 286.349
• InChiKey: BTVDJWXGFPNPDZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  78
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  p-Toluolsulfonsaeure-(4-acetoxy-butylester) 在 四丁基亚硝酸铵 作用下， 以 甲苯 为溶剂， 反应 2.5h， 以48%的产率得到4-硝基丁基乙酸酯
  参考文献：
  名称：

  Easy and direct conversion of tosylates and mesylates into nitroalkanes

  摘要：

  对苯磺酸基和甲磺酸基直接通过与四丁基铵亚硝酸盐（TBAN）在温和条件下处理，转化为相应的硝基烷。

  DOI：

  10.3762/bjoc.9.58
• 作为产物：
  描述：

  四氢呋喃 、 对甲基苯磺酸乙酸酐 生成 p-Toluolsulfonsaeure-(4-acetoxy-butylester)
  参考文献：
  名称：

  Mixed sulfonic-carboxylic anhydrides. II. Reactions with aliphatic ethers and amines

  摘要：

  DOI：

  10.1021/jo00803a010

文献信息

• Nickel/Cobalt-Catalyzed C(sp³)–C(sp³) Cross-Coupling of Alkyl Halides with Alkyl Tosylates
  作者：Kimihiro Komeyama、Takuya Michiyuki、Itaru Osaka

  DOI：10.1021/acscatal.9b03352

  日期：2019.10.4

  The C(sp3)–C(sp3) cross-coupling of alkyl halides with alkyl tosylates has been developed by employing a combination of nickel and nucleophilic cobalt catalysts in the presence of a manganese reductant. This method provides a straightforward route to a diverse set of not only secondary–primary but also primary–primary C(sp3)–C(sp3) linkages under mild conditions without using alkyl-metallic reagents

  烷基卤化物与甲苯磺酸烷基酯的C（sp 3）–C（sp 3）交叉偶联是通过在锰还原剂存在下使用镍和亲核钴催化剂的组合来开发的。这种方法为在温和条件下不使用烷基金属试剂的情况下，不仅可以实现二级（一级）连接，而且还可以一级至一级（一级）C（sp 3）-C（sp 3）连接提供了直接的途径。机理研究表明，烷基卤化物和烷基甲苯磺酸盐均可形成烷基。另外，交叉偶联可用于组蛋白脱乙酰基酶抑制剂Vorinostat的短期合成。
• OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM
  申请人：SUZUKI Hiroyuki

  公开号：US20090202921A1

  公开（公告）日：2009-08-13

  The present invention provides an optical recording composition comprising at least one compound denoted by general formula (I) and a holographic recording medium comprising a recording layer, wherein the recording layer comprises at least one compound denoted by general formula (I). In general formula (I), each of A 1 and A 2 independently denotes —CR 4 R 5 —, —O—, —NR 6 —, —S—, or —C(═O)—, each of R 4 , R 5 , and R 6 independently denotes a hydrogen atom or a substituent, R 1 denotes a substituent, n denotes an integer ranging from 0 to 4, each of R 2 and R 3 independently denotes a substituent having a Hammett substituent constant, σp value, of greater than 0, R 2 and R 3 do not form a ring structure by bonding together, and at least one from among R 1 , R 2 , R 3 , A 1 , and A 2 comprises at least one polymerizable group.