N,N-diphenyl-4′-(1,2,2-triphenylvinyl)-[1,1′-biphenyl]-4-amine | 1296787-76-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-diphenyl-4′-(1,2,2-triphenylvinyl)-[1,1′-biphenyl]-4-amine
• 英文别名: 1-[4'-(diphenylamino)biphenyl-4-yl]-1,2,2-triphenylethene；TPATPE；N,N-diphenyl-4-[4-(1,2,2-triphenylethenyl)phenyl]aniline
• CAS: 1296787-76-2
• 化学式: C₄₄H₃₃N
• 分子量: 575.753
• InChiKey: MQKYCWLFWFVSLX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.8
• 重原子数：
  45
• 可旋转键数：
  8
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N,N-diphenyl-4′-(1,2,2-triphenylvinyl)-[1,1′-biphenyl]-4-amine 、 N,N-二甲基甲酰胺 在 三氯氧磷 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 25.0h， 以67%的产率得到4-(phenyl(4′-(1,2,2-triphenylvinyl)-[1,1′-biphenyl]-4-yl)amino)-benzaldehyde
  参考文献：
  名称：

  Synthesis, characterization, electrochemistry, and photophysical studies of triarylamine-containing zinc(ii) diimine bis-thiolate complexes

  摘要：

  一系列含有三芳胺的Zn（II）二亚胺双硫酸盐配合物被合成并通过1H NMR光谱、FAB质谱和令人满意的元素分析进行了表征。

  DOI：

  10.1039/c5dt02920a
• 作为产物：
  描述：

  (4-(1,2,2-三苯基乙烯基)苯基)硼酸 、 4-溴三苯胺 在 四(三苯基膦)钯 、 sodium carbonate 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 40.0h， 以71%的产率得到N,N-diphenyl-4′-(1,2,2-triphenylvinyl)-[1,1′-biphenyl]-4-amine
  参考文献：
  名称：

  Synthesis, characterization, electrochemistry, and photophysical studies of triarylamine-containing zinc(ii) diimine bis-thiolate complexes

  摘要：

  一系列含有三芳胺的Zn（II）二亚胺双硫酸盐配合物被合成并通过1H NMR光谱、FAB质谱和令人满意的元素分析进行了表征。

  DOI：

  10.1039/c5dt02920a

文献信息

• Tuning the Electronic Nature of Aggregation-Induced Emission Luminogens with Enhanced Hole-Transporting Property
  作者：Yang Liu、Shuming Chen、Jacky W. Y. Lam、Ping Lu、Ryan T. K. Kwok、Faisal Mahtab、Hoi Sing Kwok、Ben Zhong Tang

  DOI：10.1021/cm2003269

  日期：2011.5.24

  hole-transporting material but suffers aggregation-caused emission quenching in the solid state. Tetraphenylethene (TPE), on the other hand, is an archetypal luminogen that shows the phenomenon of aggregation-induced emission (AIE). In this work, TPA is attached to the TPE core as peripheral group to generate new AIE luminogens with enhanced hole-transporting property. The TPA-TPE adducts, named 1-[4′-(diphenyl

  三苯胺（TPA）是一种众所周知的空穴传输材料，但在固态下会发生聚集引起的发射猝灭。另一方面，四苯乙炔（TPE）是原型发光剂，显示出聚集诱导发射（AIE）现象。在这项工作中，TPA作为外围基团附着在TPE核心上，以产生具有增强的空穴传输性能的新型AIE发光剂。TPA-TPE加合物，称为1- [4'-（二苯氨基）联苯-4-基] -1,2,2-三苯乙烯（TPATPE）和1,2-双[4'-（二苯氨基）联苯-4-通过将4-（二苯基氨基）苯基硼酸与1-（4-溴苯基）-1,2,2-三苯基乙烯和1,2-双（ 4-溴苯基）-1，2-二苯基乙烯。尽管杂化分子在溶液状态下实际上是不发光的，但它们在不良溶剂和薄膜中的聚集体却发出强烈的荧光，其荧光量子产率高达100％。TPATPE和2TPATPE均具有热稳定性和形态学稳定性，显示出很高的热降解率（T d高达430°C）和玻璃化转变温度（T g = 119°C）。构
• Luminogens for biological applications
  申请人：THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY

  公开号：US11186586B2

  公开（公告）日：2021-11-30

  A compound comprises a donor and an acceptor, wherein at least one donor (“D”) and at least one acceptor (“A”) may be arranged in an order of D-A; D-A-D; A-D-A; D-D-A-D-D; A-A-D-A-A; D-A-D-A-D; and A-D-A-D-A. The compound may be selected from the group consisting of: MTPE-TP, MTPE-TT, TPE-TPA-TT, PTZ-BT-TPA, NPB-TQ, TPE-TQ-A, MTPE-BTSe, DCDPP-2TPA, DCDPP-2TPA4M, DCDP-2TPA, DCDP-2TPA4M, TTS, ROpen-DTE-TPECM, and RClosed-DTE-TPECM. The compound may be used as a probe and may be functionalized with special targeted groups to image biological species. As non-limiting examples, the compound may be used in cellular cytoplasms or tissue imaging, blood vessel imaging, in vivo fluorescence imaging, brain vascular imaging, sentinel lymph node mapping, and tumor imaging, and the compound may be used as a photoacoustic agent.

  一种化合物由供体和受体组成，其中至少一个供体（"D"）和至少一个受体（"A"）可以按照 D-A；D-A-D；A-D-A；D-D-A-D-D；A-A-D-A；D-A-D-A-D；和 A-D-A-D-A 的顺序排列。该化合物可选自由以下组成的组：MTPE-TP、MTPE-TT、TPE-TPA-TT、PTZ-BT-TPA、NPB-TQ、TPE-TQ-A、MTPE-BTSe、DCDPP-2TPA、DCDPP-2TPA4M、DCDP-2TPA、DCDP-2TPA4M、TTS、ROpen-DTE-TPECM 和 RClosed-DTE-TPECM。化合物可用作探针，也可与特殊的靶向基团官能化，以成像生物物种。作为非限制性实例，该化合物可用于细胞胞浆或组织成像、血管成像、体内荧光成像、脑血管成像、前哨淋巴结绘图和肿瘤成像，该化合物还可用作光声剂。
• THERANOSTIC AGENTS
  申请人：THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY

  公开号：US20200147078A1

  公开（公告）日：2020-05-14

  A theranostic agent can be used in both photoacoustic imaging (PAI) and photothermal therapy (PTT) applications. The theranostic agent can include a small molecule, organic compound with absorption in the near-infrared (NIR) interrogation window (700-900 nm). The compound can be a biocompatible organic nanoparticle (ONP). The theranostic agent can be effectively used in PAI and PAI-guided PTT applications. The theranostic agent can be administered to a patient to locate a tumor site in the patient using in vivo imaging techniques. Once the tumor site has been determined, the tumor site can be irradiated with near-infrared light to stop or inhibit the growth of the tumor.
• LUMINOGENS FOR BIOLOGICAL APPLICATIONS
  申请人：THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY

  公开号：US20220048923A1

  公开（公告）日：2022-02-17

  A compound comprises a donor and an acceptor, wherein at least one donor (“D”) and at least one acceptor (“A”) may be arranged in an order of D-A; D-A-D; A-D-A; D-D-A-D-D; A-A-D-A-A; D-A-D-A-D; and A-D-A-D-A. The compound may be selected from the group consisting of: MTPE-TP, MTPE-TT, TPE-TP A-TT, PTZ-BT-TP A, NPB-TQ, TPE-TQ-A, MTPE-BTSe, DCDPP-2TP A, DCDPP-2TPA4M, DCDP-2TPA, DCDP-2TPA4M, TTS, ROpen-DTE-TPECM, and RClosed-DTE-TPECM. The compound may be used as a probe and may be functionalized with special targeted groups to image biological species. As non-limiting examples, the compound may be used in cellular cytoplasms or tissue imaging, blood vessel imaging, in vivo fluorescence imaging, brain vascular imaging, sentinel lymph node mapping, and tumor imaging, and the compound may be used as a photoacoustic agent.