7-Prop-2-enoxyheptan-1-ol | 880148-67-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 7-Prop-2-enoxyheptan-1-ol
• CAS: 880148-67-4
• 化学式: C₁₀H₂₀O₂
• 分子量: 172.268
• InChiKey: RLQXDVTXZPVRMT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  12
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  7-Prop-2-enoxyheptan-1-ol 、 对甲苯磺酰氯 以85%的产率得到Toluene-4-sulfonic acid 7-allyloxy-heptyl ester
  参考文献：
  名称：

  Probing structure/affinity relationships for the Plasmodium falciparum hexose transporter with glucose derivatives

  摘要：

  A series of 3-O-substituted glucose derivatives was prepared with alkyl, alkenyl, aromatic and ferrocenic substituents; to vary lipophilicity and hydrogen bonding ethylenedioxy and perfluorinated fragments were also introduced. Apparent affinities for the Plasmodium falciparum hexose transporter (PfHT) were determined after heterologous expression in Xenopus oocytes, with highest affinities for compounds with C8-C13 lipophilic chains. As no derivatives show significant affinity for the mammalian glucose transporter (GLUT1), these structure/affinity assays contribute to design of potent PfHT inhibitors and eventual development of antimalarials. (C) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.11.068
• 作为产物：
  描述：

  1,7-庚二醇 、 3-溴丙烯 在 sodium hydride 作用下， 生成 7-Prop-2-enoxyheptan-1-ol
  参考文献：
  名称：

  Probing structure/affinity relationships for the Plasmodium falciparum hexose transporter with glucose derivatives

  摘要：

  A series of 3-O-substituted glucose derivatives was prepared with alkyl, alkenyl, aromatic and ferrocenic substituents; to vary lipophilicity and hydrogen bonding ethylenedioxy and perfluorinated fragments were also introduced. Apparent affinities for the Plasmodium falciparum hexose transporter (PfHT) were determined after heterologous expression in Xenopus oocytes, with highest affinities for compounds with C8-C13 lipophilic chains. As no derivatives show significant affinity for the mammalian glucose transporter (GLUT1), these structure/affinity assays contribute to design of potent PfHT inhibitors and eventual development of antimalarials. (C) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.11.068

文献信息

• Chlorotrifluoroethylene based copolymer suitable as paint vehicle
  申请人：CENTRAL GLASS COMPANY, LIMITED

  公开号：EP0462603A1

  公开（公告）日：1991-12-27

  The invention provides a copolymer of 25-75 mol% of chlorotrifluoroethylene, 10-70 mol% of a vinyl or isopropenyl ester of fatty acid and 3-75 mol% of a hydroxyl-containing allyl ether represented by where n is an integer from 3 to 8, and 0-40 mol% of optional monomer(s) such as, e.g., vinylacetic acid or an acrylate. The copolymer is soluble in various organic solvents and curable with a polyisocyanate or a melamine resin, and the cured copolymer is excellent in weatherability, water resistance, chemical resistance and abrasion resistance. The copolymer is suitable for use as a paint vehicle.

  本发明提供了一种由 25-75 摩尔%的三氟氯乙烯、10-70 摩尔%的脂肪酸乙烯基酯或异丙烯基酯和 3-75 摩尔%的含羟基烯丙基醚组成的共聚物，其代表形式为 其中 n 为 3 至 8 的整数，以及 0-40 摩尔%的任选单体，如乙烯基乙酸或丙烯酸酯。该共聚物可溶于各种有机溶剂，并可与多异氰酸酯或三聚氰胺树脂固化，固化后的共聚物具有优异的耐候性、耐水性、耐化学性和耐磨性。这种共聚物适合用作涂料载体。
• THERMOSET PAINT COMPOSITIONS
  申请人：BASF Coatings Aktiengesellschaft

  公开号：EP0822966B1

  公开（公告）日：1999-06-30
• US5200480A
  申请人：——

  公开号：US5200480A

  公开（公告）日：1993-04-06
• US6689839B1
  申请人：——

  公开号：US6689839B1

  公开（公告）日：2004-02-10
• [EN] THERMOSET PAINT COMPOSITIONS<br/>[FR] COMPOSITIONS DE PEINTURES THERMODURCISSABLES
  申请人：BASF LACKE + FARBEN AG

  公开号：WO1996034064A1

  公开（公告）日：1996-10-31

  (EN) Thermoset paint compositions with which paint films can be formed which have excellent acid resistance, abrasion resistance and adhesion, and with which the water repelling properties and staining resistance can be retained for a longer period of time than with the conventional fluorine resin based paint films, are obtained. Constitution: Thermoset paint film compositions which contain (a) from 20 to 80 % by weight of fluorine containing copolymer, comprising fluoro-olefin and vinyl based monomer, of which the solubility parameter value is from 9.0 to 10.5 and the hydroxy group value is within the range from 60 to 150 mgKOH/g; (b) from 20-80 % by weight of vinyl based (co)polymer, comprising vinyl based monomer which contains at least 10 % by weight of monomer which can be repesented by formula (1), of which the solubility parameter is from 9.0 to 10.5 and the hydroxy group value is within the range from 60 to 150 mgKOH/g; (c) from 5 to 40 % by weight of alkyl etherified melanine resin; and (d) from 2 to 40 % by weight of blocked polyisocyanate compound, and with which the glass transition temperature of the paint film after hardening is at least 50 °C. In formula (1), R1 to R5 each independently represent H or methyl group, i is 0-2, j is 0 or 1, k is 0-3, m is 0-3 and n is 0-10.(FR) L'invention concerne des compositions de peintures thermodurcissables permettant de former des couches de peinture présentant une grande résistance aux acides, une grande résistance à l'abrasion, une adhérence élevée, et conservant leurs caractéristiques hydrophobes et leur résistance à la coloration plus longtemps que les couches de peintures à base de résine fluorée classiques. Ces compositions de peintures thermodurcissables comprennent: (a) de 20 à 80 % en poids de copolymère contenant du fluor, comprenant un monomère à base de vinyle et de fluoro-oléfine, dont l'indice de solubilité est compris entre 9,0 et 10,5 et l'indice hydroxyle est compris entre 60 et 150 mgKOH/g; (b) de 20 à 80 % en poids d'un (co)polymère à base de vinyle, comprenant un monomère à base de vinyle contenant au moins 10 % en poids d'un monomère pouvant être représenté par la formule (1), dont l'indice de solubilité est compris entre 9,0 et 10,5 et l'indice hydroxyle est compris entre 60 et 150 mgKOH/g; (c) de 5 à 40 % en poids d'une résine de mélamine éthérifiée par alkyle; et (d) de 2 à 40 % en poids d'un composé polyisocyanate séquencé. La température de transition vitreuse d'une couche formée à l'aide d'une peinture de ladite composition est d'au moins 50 °C. Dans ladite formule (1), R1 à R5 représentent chacun indépendamment un groupe H ou méthyle, i vaut 0-2, j vaut 0 ou 1, k vaut 0-3, m vaut 0-3 et n vaut 0-10.