4,7-Diamino-2-phenyl-benzotriazol | 21036-43-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4,7-Diamino-2-phenyl-benzotriazol
• 英文别名: 2-phenyl-2H-benzotriazole-4,7-diamine；2-Phenylbenzotriazole-4,7-diamine
• CAS: 21036-43-1
• 化学式: C₁₂H₁₁N₅
• 分子量: 225.253
• InChiKey: NTRSDEYGHGJNLF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  82.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] WATER-SOLUBLE POLYMERIC DYES<br/>[FR] COLORANTS POLYMÈRES HYDROSOLUBLES
  申请人：BECTON DICKINSON CO

  公开号：WO2018111774A1

  公开（公告）日：2018-06-21

  Water soluble polymeric dyes and polymeric tandem dyes are provided. The polymeric dyes include a water solvated light harvesting multichromophore having a conjugated segment of aryl or heteroaryl co-monomers including branched non-ionic water soluble groups (WSG) comprising two or more water soluble polymers. In some cases, the branched non-ionic water soluble groups (WSG) of the present disclosure are capable of imparting solubility in water in excess of 50 mg/mL to the multichromophore. The polymeric tandem dyes further include a signaling chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. Also provided are aggregation-resistant labelled specific binding members that include the subject water soluble polymeric dyes. Methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule in which the subject polymeric dyes find use are also provided. Systems and kits for practicing the subject methods are also provided.