9-hydroxy-10-nitro-octadecanoic acid | 88127-48-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 9-hydroxy-10-nitro-octadecanoic acid
• 英文别名: 9-Hydroxy-10-nitro-octadecansaeure；λ-Nitro-ι-oxy-stearinsaeure；9-Hydroxy-10-nitrooctadecanoic acid；9-hydroxy-10-nitrooctadecanoic acid
• CAS: 88127-48-4
• 化学式: C₁₈H₃₅NO₅
• 分子量: 345.48
• InChiKey: HTHBLMOFSNPJLE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  24
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  103
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  油酸 在 dinitrogen tetraoxide 、 Petroleum ether 作用下， 生成 9-hydroxy-10-nitro-octadecanoic acid 、 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Jegorow, Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1903, vol. 35, p. 975

  摘要：

  DOI：

文献信息

• BIOPASSIVATING MEMBRANE STABILIZATION BY MEANS OF NITROCARBOXYLIC ACID-CONTAINING PHOSPHOLIPIDS IN PREPARATIONS AND COATINGS
  申请人：Dietz Ulrich

  公开号：US20140099354A1

  公开（公告）日：2014-04-10

  The present invention relates to nitro-carboxylic acid (s)-containing phospholipids, to be used for coating of medical devices such as stents, catheter balloons, wound pads or surgical suture material and for bio-passivating compositions, such as rinses, waterproofing solutions, coating solutions, cryoprotection solutions, cold preservation media, lyoprotection solutions, contrast media solutions, preservation and reperfusion solutions containing these compounds as well as preparing solutions thereof and coating medical devices as well as their uses.

  本发明涉及一种含硝基羧酸（s）的磷脂，用于涂覆医疗器械，如支架、导管球囊、伤口垫或外科缝合材料，以及用于生物钝化组合物，如漱口液、防水溶液、涂层溶液、冷冻保护溶液、冷藏介质、冻干保护溶液、造影介质溶液、含有这些化合物的保存和再灌注溶液，以及制备这些溶液和涂覆医疗器械以及它们的用途。
• BIOPASSIVIERENDE MEMBRANSTABILISATION MITTELS NITROCARBONSÄUREN-ENTHALTENDEN PHOSPHOLIPIDEN IN ZUBEREITUNGEN UND BESCHICHTUNGEN
  申请人：Dietz, Ulrich

  公开号：EP2717864A1

  公开（公告）日：2014-04-16
• USE OF NITROCARBOXYLIC ACIDS FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF AGGRESSIVE HEALING PATTERNS
  申请人：Dietz Ulrich

  公开号：US20130039956A1

  公开（公告）日：2013-02-14

  The invention is directed to implants and medical devices having at least one layer which contains at least one nitrocarboxylic acid. These implants and medical devices shall be used for the prophylaxis and treatment of aggressive healing patterns. Furthermore, this invention relates to the use of nitrocarboxylic acids and their pharmaceutically acceptable salts as a therapeutic agent for the prophylaxis and treatment of a pathophysiological or non-physiological healing pattern due to exposure to a physical, chemical or thermal irritant of tissues, cells or organelles.
• [EN] USE OF NITROCARBOXYLIC ACIDS FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF AGGRESSIVE HEALING PATTERNS<br/>[FR] UTILISATION D'ACIDES NITROCARBOXYLIQUES POUR LE TRAITEMENT, LE DIAGNOSTIC ET LA PROPHYLAXIE DE MOTIFS DE CICATRISATION AGRESSIFS
  申请人：DIETZ ULRICH

  公开号：WO2011113507A2

  公开（公告）日：2011-09-22

  The invention is directed to implants and medical devices having at least one layer which contains at least one nitrocarboxylic acid. These implants and medical devices shall be used for the prophylaxis and treatment of aggressive healing patterns. Furthermore, this invention relates to the use of nitrocarboxylic acids and their pharmaceutically acceptable salts as a therapeutic agent for the prophylaxis and treatment of a pathophysiological or non-physiological healing pattern due to exposure to a physical, chemical or thermal irrtant of tissues, cells or organelles.
• [DE] BIOPASSIVIERENDE MEMBRANSTABILISATION MITTELS NITROCARBONSÄUREN-ENTHALTENDEN PHOSPHOLIPIDEN IN ZUBEREITUNGEN UND BESCHICHTUNGEN<br/>[EN] BIOPASSIVATING MEMBRANE STABILIZATION BY MEANS OF NITROCARBOXYLIC ACID-CONTAINING PHOSPHOLIPIDS IN PREPARATIONS AND COATINGS<br/>[FR] STABILISATION DE MEMBRANE PAR BIOPASSIVATION AU MOYEN DE PHOSPHOLIPIDES CONTENANT DES ACIDES NITROCARBOXYLIQUES DANS DES PRÉPARATIONS ET DES REVÊTEMENTS
  申请人：DIETZ ULRICH

  公开号：WO2012168342A1

  公开（公告）日：2012-12-13

  Die vorliegende Erfindung betrifft Nitrocarbonsäure(n)-enthaltende Phospholipide, mit besagten Verbindungen beschichtete Medizinprodukte wie beispielsweise Stents, Katheterballons, Wundeinlagen oder chirurgisches Nahtmaterial und biopassivierende Zusammensetzungen, Spüllösungen, Imprägnierlösungen, Beschichtungslösungen, Cryoprotektionslösungen, Kältekonservierungsmedien, Lyoprotektionslösungen, Kontrastmittellösungen, Konservierungslösungen und Perfusionslösungen enthaltend diese Verbindungen sowie die Herstellung dieser Lösungen und der beschichteten Medizinprodukte und deren Verwendungen.