1,2-Bis(4,5-diphenyloxazol-2-YL)ethane | 2806364-75-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1,2-Bis(4,5-diphenyloxazol-2-YL)ethane
• 英文别名: 2-[2-(4,5-diphenyl-1,3-oxazol-2-yl)ethyl]-4,5-diphenyl-1,3-oxazole
• CAS: 2806364-75-8
• 化学式: C₃₂H₂₄N₂O₂
• 分子量: 468.5
• InChiKey: FIWMRQKUYCUIKK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.7
• 重原子数：
  36
• 可旋转键数：
  7
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  52.1
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• PHARMACEUTICAL MULTIMERIC PARTICLES, AND MANUFACTURING METHOD FOR SAME
  申请人：Kasai Hitoshi

  公开号：US20130096097A1

  公开（公告）日：2013-04-18

  [Problem] The purpose of the present invention is to provide organic particles containing pharmaceutical particles of which the particles are small and the particle size distribution is narrow, and a manufacturing method for the same. [Solution] Provided are pharmaceutical multimeric particles of which the particles are small and the particle size distribution is narrow and which are characterized in being obtained by pouring into water a solution of a pharmaceutical multimer dissolved in a water-miscible organic solvent, and a manufacturing method for the pharmaceutical multimeric particles. Pharmaceutical dimeric particles thereof are characterized in being obtained by pouring into water a solution of a compound represented by general formula (I) dissolved in a water-miscible organic solvent.

  [问题] 本发明的目的是提供含有药用颗粒的有机颗粒，其颗粒小且颗粒尺寸分布窄，以及其制备方法。[解决方案] 提供了药用多聚体颗粒，其颗粒小且颗粒尺寸分布窄，其特征在于通过将溶解在水相溶性有机溶剂中的药用多聚体溶液倒入水中获得，并提供了药用多聚体颗粒的制备方法。其药用二聚体颗粒的特征在于通过将溶解在水相溶性有机溶剂中的一种由通式（I）表示的化合物溶液倒入水中获得。