1-Chloro-3-(methoxymethyl)-2-nitrobenzene | 257871-21-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Chloro-3-(methoxymethyl)-2-nitrobenzene
• CAS: 257871-21-9
• 化学式: C8H8ClNO3
• 分子量: 201.61
• InChiKey: MGLZLNQEGILVQU-UHFFFAOYSA-N

物化性质

• 沸点：
  265.9±25.0 °C(Predicted)
• 密度：
  1.322±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  55
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  sodium;hydride 、 4,6-dimethoxy-2-pyrimidinylacetonitrile 、 氢气 、 1-Chloro-3-(methoxymethyl)-2-nitrobenzene 、 、 盐酸 在 ice water 、 乙酸乙酯 、 氯化钠 、 水 、 乙醇 、 异丙醚 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 12.0h， 以to obtain 31 g (yield: 64%) of 2-(4,6-dimethoxypyrimidine-2-yl)-2-(3-methoxymethyl-2-nitrophenyl)acetonitrile as a reddish brown powder (melting point: 112 to 113° C)的产率得到2-(4,6-dimethoxypyrimidin-2-yl)-2-(3-methoxymethyl-2-nitro-phenyl)acetonitrile
  参考文献：
  名称：

  Di- or tri-fluoromethanesulfonyl anilide derivatives, process for the preparation of them and herbicides containing them as the active ingredient

  摘要：

  本发明提供了一种新型化合物，能够有效地去除包括稻田中难以控制的杂草在内的各种杂草，并且对哺乳动物安全；一种其生产工艺；一种以该化合物为活性成分的除草剂；以及在该工艺中使用的新型原料化合物。本发明涉及一种二氟甲烷磺酰苯胺衍生物或三氟甲烷磺酰苯胺衍生物，其通式如下：（其中R1是氢原子、烷基或烷氧基烷基；当R1是氢原子或烷基时，R2是氢原子；当R1是烷氧基烷基时，R2是氢原子或氟原子），或其盐，上述衍生物和盐具有除草活性。

  公开号：

  US06458748B1

文献信息

• METHOD FOR PRODUCING NITROBENZENE COMPOUND
  申请人：Tani Shinki

  公开号：US20140163256A1

  公开（公告）日：2014-06-12

  A method for producing a nitrobenzene compound represented by general formula (2), wherein R 1 and R 5 are the same or different, and each is a halogen atom or another functional group, and R 2 , R 3 , and R 4 are the same or different, and each is a hydrogen atom or another functional group, comprises oxidizing an aniline compound represented by general formula (1), wherein R 1 , R 2 , R 3 , R 4 , and R 5 are the same as described above, with hydrogen peroxide in the presence of a tungsten compound under an acidic condition, followed by oxidation with hydrogen peroxide under a neutral to alkaline condition.

  一种用于制备由通式（2）表示的硝基苯化合物的方法，其中R1和R5相同或不同，每个是卤素原子或另一个官能团，而R2、R3和R4相同或不同，每个是氢原子或另一个官能团，包括在酸性条件下在钨化合物存在下用过氧化氢氧化由通式（1）表示的苯胺化合物，其中R1、R2、R3、R4和R5与上述相同，随后在中性至碱性条件下用过氧化氢氧化。
• DI- OR TRI-FLUOROMETHANESULFONYL ANILIDE DERIVATIVES, PROCESS FOR THE PREPARATION OF THEM AND HERBICIDES CONTAINING THEM AS THE ACTIVE INGREDIENT
  申请人：IHARA CHEMICAL INDUSTRY CO., LTD.

  公开号：EP1101760A1

  公开（公告）日：2001-05-23

  The present invention provides a novel compound which is effective for the removal of a wide variety of weeds including difficult-to-control weeds emerging in paddy field and which is safe to mammals; a process for production thereof; a herbicide containing the compound as an active ingredient; and novel raw material compounds used in said process. The present invention relates to a di- or trifluoromethanesulfonyl anilide derivative represented by the following general formula: (wherein R1 is a hydrogen atom, an alkyl group or an alkoxyalkyl group; and R2 is a hydrogen atom when R1 is a hydrogen atom or an alkyl group, and is a hydrogen atom or a fluorine atom when R1 is an alkoxyalkyl group), or a salt thereof, both of said derivative and said salt having a herbicidal activity.

  本发明提供了一种新型化合物，该化合物可有效除去多种杂草，包括水田中出现的难以控制的杂草，且对哺乳动物安全；其生产工艺；含有该化合物作为活性成分的除草剂；以及用于上述工艺的新型原料化合物。 本发明涉及由以下通式代表的二氟或三氟甲磺酰苯胺衍生物： (其中 R1 是氢原子、烷基或烷氧基烷基；当 R1 是氢原子或烷基时，R2 是氢原子；当 R1 是烷氧基烷基时，R2 是氢原子或氟原子），或其盐，所述衍生物和所述盐均具有除草活性。
• Trifluoromethanesulfonyl anilide derivatives, process for the preparation of them and herbicides containing them as the active ingredient
  申请人：IHARA CHEMICAL INDUSTRY CO., LTD.

  公开号：EP1361218A1

  公开（公告）日：2003-11-12

  The present invention provides a novel compound which is effective for the removal of a wide variety of weeds including difficult-to-control weeds emerging in paddy field and which is safe to mammals; a process for production thereof; a herbicide containing the compound as an active ingredient; and novel raw material compounds used in said process. The present invention relates to a trifluoromethanesulfonyl anilide derivative represented by the following general formula: (wherein R1 is an alkoxyalkyl group; and R2 is a fluorine atom), or a salt thereof, both of said derivative and said salt having a herbicidal activity.

  本发明提供了一种新型化合物，它能有效除去多种杂草，包括水田中出现的难以控制的杂草，并且对哺乳动物安全；其生产工艺；含有该化合物作为活性成分的除草剂；以及用于所述工艺的新型原料化合物。 本发明涉及由以下通式代表的三氟甲磺酰苯胺衍生物： (其中 R1 为烷氧基烷基；R2 为氟原子）或其盐，所述衍生物和所述盐均具有除草活性。
• DIFLUOROMETHANESULFONYL ANILIDE DERIVATIVES, PROCESS FOR THE PREPARATION OF THEM AND HERBICIDES CONTAINING THEM AS THE ACTIVE INGREDIENT
  申请人：IHARA CHEMICAL INDUSTRY CO., LTD.

  公开号：EP1101760B1

  公开（公告）日：2003-10-15
• NITROBENZENE COMPOUND MANUFACTURING METHOD
  申请人：Kumiai Chemical Industry Co., Ltd.

  公开号：EP2754651B1

  公开（公告）日：2017-12-06