1-Butyl-5-propyl-1,2,3-triazol | 15886-31-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-Butyl-5-propyl-1,2,3-triazol
• 英文别名: 1-butyl-5-propyl-1H-[1,2,3]triazole；1-Butyl-5-propyltriazole
• CAS: 15886-31-4
• 化学式: C₉H₁₇N₃
• 分子量: 167.254
• InChiKey: BTFMDLCPAOUJEV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  30.7
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• TRIAZOLE-CROSSLINKED AND THIOETHER-CROSSLINKED PEPTIDOMIMETIC MACROCYCLES
  申请人：Aileron Therapeutics, Inc.

  公开号：US20130210745A1

  公开（公告）日：2013-08-15

  Provided herein are peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease.

  本文提供了肽类模拟大环化合物以及利用这些大环化合物治疗疾病的方法。
• TRIAZOLE MACROCYCLE SYSTEMS
  申请人：Aileron Therapeutics, Inc.

  公开号：US20160031936A1

  公开（公告）日：2016-02-04

  The present invention provides novel peptidomimetic macrocycles and methods for their preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and kits useful in their production.

  本发明提供了新型肽类模拟大环以及其制备和使用方法，还提供了氨基酸类似物和大环形成连接剂，以及在它们的生产中有用的试剂盒。
• Triazole Macrocycle Systems
  申请人：Nash Huw M.

  公开号：US20080262200A1

  公开（公告）日：2008-10-23

  The present invention provides novel peptidomimetic macrocycles and methods for their preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and kits useful in their production.
• Therapeutic peptidomimetic macrocycles
  申请人：Nash Huw M.

  公开号：US20090275519A1

  公开（公告）日：2009-11-05

  The present invention provides biologically active peptidomimetic macrocycles for the treatment of cell proliferative disorders such as cancer and immunoproliferative disease.
• BIOLOGICALLY ACTIVE PEPTIDOMIMETIC MACROCYCLES
  申请人：Nash Huw M.

  公开号：US20090326192A1

  公开（公告）日：2009-12-31

  The present invention provides biologically active peptidomimetic macrocycles with improved properties relative to their corresponding polypeptides. The invention additionally provides methods of preparing and using such macrocycles, for example in therapeutic applications.