(1,10-phenathroline)Pd(CH2CH(CH2CH2CHCHCOOBu)N-tosyl) | 918160-56-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: (1,10-phenathroline)Pd(CH2CH(CH2CH2CHCHCOOBu)N-tosyl)
• CAS: 918160-56-2
• 化学式: C₃₀H₃₃N₃O₄PdS
• 分子量: 638.096
• InChiKey: DWAQNJNEKWYLLR-SQKCAUCHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  (1,10-phenathroline)Pd(CH2CH(CH2CH2CHCHCOOBu)N-tosyl) 在 copper(l) iodide 作用下， 以 四氢呋喃 为溶剂， 以54%的产率得到(1,10-phenathroline)Pd(CH(COOBu)CH(CH2)CH2CH2CHN-tosyl)
  参考文献：
  名称：

  Synthesis and Reactivity of Azapalladacyclobutanes

  摘要：

  N-Sulfonyl aziridines undergo oxidative addition to palladium(0) complexes generated in situ from mixtures of Pd-2(dba)(3) and 1,10-phenanthroline. The resulting azapalladacyclobutane complexes undergo intramolecular carbopalladation in the presence of copper(I) iodide to afford azapalladabicyclo-[3.2.1] octanes. A deuterium-labeling experiment indicates that the oxidative addition proceeds via S(N)2-type attack of palladium(0) on the less-hindered carbon of the aziridine ring and that alkene insertion occurs in a syn fashion. The azapalladabicyclo[3.2.1] octane complexes undergo oxidative palladium-carbon bond functionalization in the presence of copper(II) bromide.

  DOI：

  10.1021/ja0660756
• 作为产物：
  描述：

  1,10-菲罗啉 、 tris(dibenzylideneacetone)dipalladium (0) 、 以 四氢呋喃 为溶剂， 以44%的产率得到(1,10-phenathroline)Pd(CH2CH(CH2CH2CHCHCOOBu)N-tosyl)
  参考文献：
  名称：

  Synthesis and Reactivity of Azapalladacyclobutanes

  摘要：

  N-Sulfonyl aziridines undergo oxidative addition to palladium(0) complexes generated in situ from mixtures of Pd-2(dba)(3) and 1,10-phenanthroline. The resulting azapalladacyclobutane complexes undergo intramolecular carbopalladation in the presence of copper(I) iodide to afford azapalladabicyclo-[3.2.1] octanes. A deuterium-labeling experiment indicates that the oxidative addition proceeds via S(N)2-type attack of palladium(0) on the less-hindered carbon of the aziridine ring and that alkene insertion occurs in a syn fashion. The azapalladabicyclo[3.2.1] octane complexes undergo oxidative palladium-carbon bond functionalization in the presence of copper(II) bromide.

  DOI：

  10.1021/ja0660756