2-(2',4'-Dinitrophenyl)imidazol | 4205-07-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-(2',4'-Dinitrophenyl)imidazol
• 英文别名: 2-(2,4-dinitro-phenyl)-1H-imidazole；2-(2,4-dinitrophenyl)-1H-imidazole
• CAS: 4205-07-6
• 化学式: C₉H₆N₄O₄
• 分子量: 234.171
• InChiKey: KYTZOBSJVCLESY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  120
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• PHENYL-AZA-BENZIMIDAZOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION
  申请人：Avanir Pharmaceuticals

  公开号：EP1546157A2

  公开（公告）日：2005-06-29
• EP1546157A4
  申请人：——

  公开号：EP1546157A4

  公开（公告）日：2007-02-28
• [EN] PHENYL-AZA-BENZIMIDAZOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION<br/>[FR] COMPOSES DE PHENYL-AZA-BENZIMIDAZOLE POUR MODULER IGE ET INHIBER LA PROLIFERATION CELLULAIRE
  申请人：AVANIR PHARMACEUTICALS

  公开号：WO2004024897A2

  公开（公告）日：2004-03-25

  The present invention is directed to small molecule inhibitors of the IgE response to allergens, which are useful in the treatment of allergy and/or asthma or any diseases where IgE is pathogenic. This invention also relates to phenyl-aza-benzimidazole molecules that are cellular proliferation inhibitors and thus are useful as anticancer agents. This invention further relates to small molecules which suppress cytokines and leukocytes.