4-[(8-Hydroxyquinolin-5-yl)methylideneamino]-1,5-dimethyl-2-phenylpyrazol-3-one | 1318239-63-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-[(8-Hydroxyquinolin-5-yl)methylideneamino]-1,5-dimethyl-2-phenylpyrazol-3-one
• CAS: 1318239-63-2
• 化学式: C₂₁H₁₈N₄O₂
• 分子量: 358.4
• InChiKey: KPWZUKBPKFGQHE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  69
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  8-羟基-5-喹啉羧醛 、 4-氨基安替比林 以 乙醇 为溶剂， 生成 4-[(8-Hydroxyquinolin-5-yl)methylideneamino]-1,5-dimethyl-2-phenylpyrazol-3-one
  参考文献：
  名称：

  8-Hydroxyquinoline-5-carbaldehyde Schiff-base as a highly selective and sensitive Al3+ sensor in weak acid aqueous medium

  摘要：

  In the paper, a novel fluorescent sensor (1) based on 8-hydroxyquinoline carbaldehyde Schiff-base was synthesized and characterized. This fluorescent sensor exhibited high selectivity for Al3+ over other metal ions with the detection limit reaching below 10(-7)M under weak acid aqueous conditions. These suggested that 1 could be served as a highly selective and sensitive fluorescence sensor for aluminum ion in acid medium. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2011.04.027