2-(1-Methyl-indol-3-yl)-4-phenyl-5-(p-chlor-phenyl)imidazol | 39237-05-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-(1-Methyl-indol-3-yl)-4-phenyl-5-(p-chlor-phenyl)imidazol
• 英文别名: 3-[5-(4-chloro-phenyl)-4-phenyl-1(3)H-imidazol-2-yl]-1-methyl-indole；3-[5-(4-chlorophenyl)-4-phenyl-1H-imidazol-2-yl]-1-methylindole
• CAS: 39237-05-3
• 化学式: C₂₄H₁₈ClN₃
• 分子量: 383.88
• InChiKey: FRKMCAXEXZEWPG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  28
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  33.6
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• 2,4,5-TRISUBSTITUTED IMIDAZOLES AND THEIR USE AS ANTI-MICROBIAL AGENTS
  申请人：Lorus Therapeutics Inc.

  公开号：EP1531674B1

  公开（公告）日：2014-06-18
• 2, 4, 5 - Trisubstituted Imidazoles And Their Use As Anti-Microbial Agents
  申请人：Al-Qawasmeh Raed

  公开号：US20070105929A1

  公开（公告）日：2007-05-10

  The present invention provides therapeutically effective 2,4,5-trisubstituted imidazole compounds, methods of preparing the same, and compositions comprising the compounds alone or in combination with other agents. The present invention further provides for the use of the compounds as anti-microbial agents. The anti-microbial properties of the compounds include anti-bacterial and/or anti-fungal activity.
• US7884120B2
  申请人：——

  公开号：US7884120B2

  公开（公告）日：2011-02-08
• US8394815B2
  申请人：——

  公开号：US8394815B2

  公开（公告）日：2013-03-12
• US8987305B2
  申请人：——

  公开号：US8987305B2

  公开（公告）日：2015-03-24