3-Phenyl-4-(4-bromphenyl)-pyrazol | 109569-19-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3-Phenyl-4-(4-bromphenyl)-pyrazol
• 英文别名: 4-(4-bromo-phenyl)-3-phenyl-1(2)H-pyrazole；4-(4-bromophenyl)-5-phenyl-1H-pyrazole
• CAS: 109569-19-9
• 化学式: C₁₅H₁₁BrN₂
• 分子量: 299.17
• InChiKey: DZSLUIIQPVBEIP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  28.7
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• INHIBITORS OF FATTY ACID AMIDE HYDROLASE
  申请人：Infinity Pharmaceuticals, Inc.

  公开号：EP2282742A1

  公开（公告）日：2011-02-16
• [EN] INHIBITORS OF FATTY ACID AMIDE HYDROLASE<br/>[FR] INHIBITEURS D'HYDROLASE D'AMIDE D'ACIDE GRAS
  申请人：INFINITY PHARMACEUTICALS INC

  公开号：WO2009126691A1

  公开（公告）日：2009-10-15

  The present invention provides compounds, and pharmaceutically acceptable compositions thereof, encompassed by any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof. The present invention also provides methods for treating an FAAH mediated disease, disorder or condition by administering a therapeutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof. Additionally, the present invention provides methods for inhibiting FAAH by administering a therapeutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof.