N-tert-butyl-1-(2-ditert-butylphosphanylcyclobuten-1-yl)methanimine | 1417705-38-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-tert-butyl-1-(2-ditert-butylphosphanylcyclobuten-1-yl)methanimine
• CAS: 1417705-38-4
• 化学式: C₁₇H₃₂NP
• 分子量: 281.422
• InChiKey: UIUIYEAPINWVHM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-tert-butyl-1-(2-ditert-butylphosphanylcyclobuten-1-yl)methanimine 以 二氯甲烷 为溶剂， 反应 28.0h， 生成 C₂₀H₃₇NPPd⁽¹⁺⁾*CF₃O₃S^(1-)
  参考文献：
  名称：

  Investigation of Steric and Electronic Features of 3-Iminophosphine-Based Palladium Catalysts for Intermolecular Hydroamination

  摘要：

  A series of (3-iminophosphine)allylpalladium triflate complexes with systematic variation of both steric and electronic features was isolated and characterized. The ability of the complexes in this series to catalyze the regioselective hydroamination of 3-methyl-1,2-butadiene with aryl amines to form solely the kinetic product was probed by observing conversion to products via NMR spectroscopy. The previously unstudied 3-iminophosphine ligand composed of a di-tert-butyl phosphine, cyclobutene backbone, and tert-butyl imine provided the most active palladium hydroamination catalyst for this transformation known to date.

  DOI：

  10.1021/om301102w
• 作为产物：
  描述：

  2-chlorocyclobut-1-enecarboxaldehyde 在 activated 4 Å molecular sieves 作用下， 以 乙醚 、 正戊烷 为溶剂， 反应 17.0h， 生成 N-tert-butyl-1-(2-ditert-butylphosphanylcyclobuten-1-yl)methanimine
  参考文献：
  名称：

  Investigation of Steric and Electronic Features of 3-Iminophosphine-Based Palladium Catalysts for Intermolecular Hydroamination

  摘要：

  A series of (3-iminophosphine)allylpalladium triflate complexes with systematic variation of both steric and electronic features was isolated and characterized. The ability of the complexes in this series to catalyze the regioselective hydroamination of 3-methyl-1,2-butadiene with aryl amines to form solely the kinetic product was probed by observing conversion to products via NMR spectroscopy. The previously unstudied 3-iminophosphine ligand composed of a di-tert-butyl phosphine, cyclobutene backbone, and tert-butyl imine provided the most active palladium hydroamination catalyst for this transformation known to date.

  DOI：

  10.1021/om301102w